# X-Ragent: Tool-Augmented Reinforcement Learning for Evidence-Grounded Chest X-Ray Reasoning

arXiv: https://arxiv.org/abs/2610.16811 · HTML: https://mlsanity.com/paper/2610.16811/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 74 of its 88 references that are in the map.
- First posted on arXiv 12 Oct 2026.

## Builds on (most cited first, 30 of 74)

- [DeepSeekMath: Pushing the Limits of Mathematical Reasoning in Open Language Models](https://mlsanity.com/paper/2402.03300/) (2024)
- [ReAct: Synergizing Reasoning and Acting in Language Models](https://mlsanity.com/paper/2210.03629/) (2022)
- [Toolformer: Language Models Can Teach Themselves to Use Tools](https://mlsanity.com/paper/2302.04761/) (2023)
- [Qwen3-VL Technical Report](https://mlsanity.com/paper/2511.21631/) (2025)
- [HuggingGPT: Solving AI Tasks with ChatGPT and its Friends in Hugging Face](https://mlsanity.com/paper/2303.17580/) (2023)
- [Multimodal Chain-of-Thought Reasoning in Language Models](https://mlsanity.com/paper/2302.00923/) (2023)
- [VLM-R1: A Stable and Generalizable R1-style Large Vision-Language Model](https://mlsanity.com/paper/2504.07615/) (2025)
- [LLaVA-CoT: Let Vision Language Models Reason Step-by-Step](https://mlsanity.com/paper/2411.10440/) (2024)
- [SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answering](https://mlsanity.com/paper/2102.09542/) (2021)
- [Uncertainty Modeling for Out-of-Distribution Generalization](https://mlsanity.com/paper/2202.03958/) (2022)
- [BiomedParse: a biomedical foundation model for image parsing of everything everywhere all at once](https://mlsanity.com/paper/2405.12971/) (2024)
- [MMedAgent: Learning to Use Medical Tools with Multi-modal Agent](https://mlsanity.com/paper/2407.02483/) (2024)
- [PromptMRG: Diagnosis-Driven Prompts for Medical Report Generation](https://mlsanity.com/paper/2308.12604/) (2023)
- [DenseFusion-1M: Merging Vision Experts for Comprehensive Multimodal Perception](https://mlsanity.com/paper/2407.08303/) (2024)
- [MedRAX: Medical Reasoning Agent for Chest X-ray](https://mlsanity.com/paper/2502.02673/) (2025)
- [PRISM: Self-Pruning Intrinsic Selection Method for Training-Free Multimodal Data Selection](https://mlsanity.com/paper/2502.12119/) (2025)
- [Pure Vision Language Action (VLA) Models: A Comprehensive Survey](https://mlsanity.com/paper/2509.19012/) (2025)
- [Enhanced Contrastive Learning with Multi-view Longitudinal Data for Chest X-ray Report Generation](https://mlsanity.com/paper/2502.20056/) (2025)
- [ReTrack: Evidence-Driven Dual-Stream Directional Anchor Calibration Network for Composed Video Retrieval](https://mlsanity.com/paper/2604.17898/) (2026)
- [LongCat-Next: Lexicalizing Modalities as Discrete Tokens](https://mlsanity.com/paper/2603.27538/) (2026)
- [AutoDrive-R2: Incentivizing Reasoning and Self-Reflection Capacity for VLA Model in Autonomous Driving](https://mlsanity.com/paper/2509.01944/) (2025)
- [mc-BEiT: Multi-choice Discretization for Image BERT Pre-training](https://mlsanity.com/paper/2203.15371/) (2022)
- [ChestX-Reasoner: Advancing Radiology Foundation Models with Reasoning through Step-by-Step Verification](https://mlsanity.com/paper/2504.20930/) (2025)
- [GEMeX: A Large-Scale, Groundable, and Explainable Medical VQA Benchmark for Chest X-ray Diagnosis](https://mlsanity.com/paper/2411.16778/) (2024)
- [Accurate Fine-Grained Segmentation of Human Anatomy in Radiographs via Volumetric Pseudo-Labeling](https://mlsanity.com/paper/2306.03934/) (2023)
- [Video-STAR: Reinforcing Open-Vocabulary Action Recognition with Tools](https://mlsanity.com/paper/2510.08480/) (2025)
- [From Editor to Dense Geometry Estimator](https://mlsanity.com/paper/2509.04338/) (2025)
- [Remote Sensing SpatioTemporal Vision-Language Models: A Comprehensive Survey](https://mlsanity.com/paper/2412.02573/) (2024)
- [Reward and Guidance through Rubrics: Promoting Exploration to Improve Multi-Domain Reasoning](https://mlsanity.com/paper/2511.12344/) (2025)
- [SD-MVS: Segmentation-Driven Deformation Multi-View Stereo with Spherical Refinement and EM optimization](https://mlsanity.com/paper/2401.06385/) (2024)

## Abstract (arXiv)

Chest X-ray (CXR) interpretation often requires integrating visual findings with task-specific evidence rather than relying on direct visual recognition alone. While tool-augmented medical agents can supply such evidence via external modules, they often lack explicit mechanisms for learning when auxiliary evidence is needed and for preventing inapplicable quantitative evidence from entering diagnostic reasoning. To address this, we propose X-Ragent, a post-training framework for tool-augmented reinforcement learning that decouples learned auxiliary-evidence seeking from validity-gated quantitative measurement acquisition for evidence-grounded CXR reasoning. We construct Rad-CoT, a 7.7K-sample corpus combining causally ordered tool-augmented trajectories with report-style diagnostic reasoning, and use it to initialize Qwen3-VL-8B via agentic supervised fine-tuning (SFT). We then optimize the policy with Group Relative Policy Optimization (GRPO) using an accuracy-gated reward that applies process-level terms for measurement consistency and auxiliary-tool cost only to correct trajectories, preventing plausible process behavior from compensating for an incorrect diagnosis. Across three CXR benchmarks, X-Ragent achieves the strongest results, including an 8.6-point improvement on the fully held-out ChestAgentBench. By seeking evidence selectively and admitting only valid measurements, X-Ragent supports more faithful and evidence-grounded CXR reasoning.
