# Med-RADIO: Reducing All Medical Domains Into One via Multi-Teacher Distillation

arXiv: https://arxiv.org/abs/2609.37682 · HTML: https://mlsanity.com/paper/2609.37682/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 41 of its 55 references that are in the map.
- First posted on arXiv 29 Sep 2026.

## Builds on (most cited first, 30 of 41)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [DINOv2: Learning Robust Visual Features without Supervision](https://mlsanity.com/paper/2304.07193/) (2023)
- [SAM 2: Segment Anything in Images and Videos](https://mlsanity.com/paper/2408.00714/) (2024)
- [DINOv3](https://mlsanity.com/paper/2508.10104/) (2025)
- [Multi-Task Learning Using Uncertainty to Weigh Losses for Scene Geometry and Semantics](https://mlsanity.com/paper/1705.07115/) (2017)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [SAM 3: Segment Anything with Concepts](https://mlsanity.com/paper/2511.16719/) (2025)
- [BiomedCLIP: a multimodal biomedical foundation model pretrained from fifteen million scientific image-text pairs](https://mlsanity.com/paper/2303.00915/) (2023)
- [Lingshu: A Generalist Foundation Model for Unified Multimodal Medical Understanding and Reasoning](https://mlsanity.com/paper/2506.07044/) (2025)
- [PMC-CLIP: Contrastive Language-Image Pre-training using Biomedical Documents](https://mlsanity.com/paper/2303.07240/) (2023)
- [Generalist Foundation Models from a Multimodal Dataset for 3D Computed Tomography](https://mlsanity.com/paper/2403.17834/) (2024)
- [Quilt-1M: One Million Image-Text Pairs for Histopathology](https://mlsanity.com/paper/2306.11207/) (2023)
- [AM-RADIO: Agglomerative Vision Foundation Model -- Reduce All Domains Into One](https://mlsanity.com/paper/2312.06709/) (2023)
- [Exploring scalable medical image encoders beyond text supervision](https://mlsanity.com/paper/2401.10815/) (2024)
- [Hulu-Med: A Transparent Generalist Model towards Holistic Medical Vision-Language Understanding](https://mlsanity.com/paper/2510.08668/) (2025)
- [RADIOv2.5: Improved Baselines for Agglomerative Vision Foundation Models](https://mlsanity.com/paper/2412.07679/) (2024)
- [Adaptive Multi-Teacher Multi-level Knowledge Distillation](https://mlsanity.com/paper/2103.04062/) (2021)
- [USFM: A Universal Ultrasound Foundation Model Generalized to Tasks and Organs towards Label Efficient Image Analysis](https://mlsanity.com/paper/2401.00153/) (2023)
- [ROCOv2: Radiology Objects in COntext Version 2, an Updated Multimodal Image Dataset](https://mlsanity.com/paper/2405.10004/) (2024)
- [A Multimodal Vision Foundation Model for Clinical Dermatology](https://mlsanity.com/paper/2410.15038/) (2024)
- [Vision Foundation Models for Computed Tomography](https://mlsanity.com/paper/2501.09001/) (2025)
- [UniMed-CLIP: Towards a Unified Image-Text Pretraining Paradigm for Diverse Medical Imaging Modalities](https://mlsanity.com/paper/2412.10372/) (2024)
- [BIOMEDICA: An Open Biomedical Image-Caption Archive, Dataset, and Vision-Language Models Derived from Scientific Literature](https://mlsanity.com/paper/2501.07171/) (2025)
- [VisionFM: a Multi-Modal Multi-Task Vision Foundation Model for Generalist Ophthalmic Artificial Intelligence](https://mlsanity.com/paper/2310.04992/) (2023)
- [Uni-Med: A Unified Medical Generalist Foundation Model For Multi-Task Learning Via Connector-MoE](https://mlsanity.com/paper/2409.17508/) (2024)
- [EyeFound: A Multimodal Generalist Foundation Model for Ophthalmic Imaging](https://mlsanity.com/paper/2405.11338/) (2024)
- [EyeCLIP: A visual-language foundation model for multi-modal ophthalmic image analysis](https://mlsanity.com/paper/2409.06644/) (2024)
- [MRI-CORE: A Foundation Model for Magnetic Resonance Imaging](https://mlsanity.com/paper/2506.12186/) (2025)

## Abstract (arXiv)

The rapid expansion of large-scale medical datasets and computational resources has driven significant progress in medical foundation models. Given the inherent heterogeneity of medical imaging modalities, current research mainly follows two paths: specialized models optimized for specific modalities, and generalist models designed to handle multiple modalities. However, medical generalist models suffer from both insufficient training data scale relative to natural image generalists and inadequate domain-specific depth relative to medical specialists. Empirically, generalist models establish a cross-modality performance baseline, while specialists define the performance ceiling within their respective domains. To elevate this baseline toward these ceilings, we propose Med-RADIO, a medical multi-teacher distillation framework that Reduces All Domains Into One by compressing complementary expertise from multiple domain-specific teachers into a unified medical vision foundation model. Our method curates both generalist and specialist teachers, allocates modality-aligned distillation streams to reorganize generalist pretraining data so it matches specialist domains, and uses a balanced loss to prevent any single teacher from dominating the distillation process. On internal and external classification benchmarks spanning five modalities, Med-RADIO improves over strong medical generalists under linear probing and remains competitive with representative specialists on most evaluated modalities. Code is available at https://github.com/CAIR-HKISI/Med-RADIO.