# Structural Alignment for Reliable Industrial AI: Bridging Physical Reality, Data, Models, and Human Intent

arXiv: https://arxiv.org/abs/2609.35400 · HTML: https://mlsanity.com/paper/2609.35400/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 26 of its 94 references that are in the map.
- First posted on arXiv 28 Sep 2026.

## Builds on (most cited first, 26 of 26)

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- [Explaining Explanations: An Overview of Interpretability of Machine Learning](https://mlsanity.com/paper/1806.00069/) (2018)
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- [Theory-guided Data Science: A New Paradigm for Scientific Discovery from Data](https://mlsanity.com/paper/1612.08544/) (2016)
- [The Debate Over Understanding in AI's Large Language Models](https://mlsanity.com/paper/2210.13966/) (2022)
- [Goal Misgeneralization in Deep Reinforcement Learning](https://mlsanity.com/paper/2105.14111/) (2021)
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- [A Survey on Uncertainty Quantification Methods for Deep Learning](https://mlsanity.com/paper/2302.13425/) (2023)
- [Consequences of Misaligned AI](https://mlsanity.com/paper/2102.03896/) (2021)
- [Mapping global dynamics of benchmark creation and saturation in artificial intelligence](https://mlsanity.com/paper/2203.04592/) (2022)
- [Can We Trust AI Benchmarks? An Interdisciplinary Review of Current Issues in AI Evaluation](https://mlsanity.com/paper/2502.06559/) (2025)
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- [A Systematic Literature Review on Hardware Reliability Assessment Methods for Deep Neural Networks](https://mlsanity.com/paper/2305.05750/) (2023)
- [Automating the Practice of Science -- Opportunities, Challenges, and Implications](https://mlsanity.com/paper/2409.05890/) (2024)
- [Benchmark datasets driving artificial intelligence development fail to capture the needs of medical professionals](https://mlsanity.com/paper/2201.07040/) (2022)
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- [Autonomics: In Search of a Foundation for Next Generation Autonomous Systems](https://mlsanity.com/paper/1911.07133/) (2019)
- [Does AI help humans make better decisions? A statistical evaluation framework for experimental and observational studies](https://mlsanity.com/paper/2403.12108/) (2024)
- [Massively Digitized Power Grid: Opportunities and Challenges of Use-inspired AI](https://mlsanity.com/paper/2205.05180/) (2022)
- [When Industry meets Trustworthy AI: A Systematic Review of AI for Industry 5.0](https://mlsanity.com/paper/2403.03061/) (2024)
- [The future of AI in critical mineral exploration](https://mlsanity.com/paper/2512.02879/) (2025)

## Abstract (arXiv)

Artificial intelligence is increasingly deployed in critical industrial domains, including healthcare, energy grids, subsurface exploration, where failures can have severe consequences for human safety, system stability, and economic outcomes. Yet AI is still evaluated primarily through benchmark accuracy, a model-centric metric that fails to capture the structural complexity and risks of real-world deployment. We propose a framework that views industrial AI reliability as a problem of structural alignment across four interacting worlds: physical, representational, machine, and human cognitive. These worlds are connected through two interfaces: digitalization, linking physical reality to computational representations, and goal encoding, translating human cognition to the machine objectives. Together, they define the space of admissible solutions. We characterize the solution space through four attributes: existence, non-uniqueness, robustness, and interpretability and show how mismatches arise at interfaces and propagate across worlds to produce reliability failures. Applications to healthcare, energy grids, and subsurface exploration illustrate that although dominant failure modes differ across domains, for example, interpretability in healthcare, robustness in energy grids, and non-uniqueness in subsurface exploration, all originate from a shared structural mechanism. By shifting the focus from model-centric evaluation to system-level alignment, this framework offers a principled foundation for assessing and governing reliability in industrial AI systems.
