# False-science induction in autonomous scientific discovery

arXiv: https://arxiv.org/abs/2609.27883 · HTML: https://mlsanity.com/paper/2609.27883/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 11 of its 48 references that are in the map.
- First posted on arXiv 20 Aug 2026.

## Builds on (most cited first, 11 of 11)

- [Understanding deep learning requires rethinking generalization](https://mlsanity.com/paper/1611.03530/) (2016)
- [Datasheets for Datasets](https://mlsanity.com/paper/1803.09010/) (2018)
- [BadNets: Identifying Vulnerabilities in the Machine Learning Model Supply Chain](https://mlsanity.com/paper/1708.06733/) (2017)
- [Co-teaching: Robust Training of Deep Neural Networks with Extremely Noisy Labels](https://mlsanity.com/paper/1804.06872/) (2018)
- [A Closer Look at Memorization in Deep Networks](https://mlsanity.com/paper/1706.05394/) (2017)
- [Poison Frogs! Targeted Clean-Label Poisoning Attacks on Neural Networks](https://mlsanity.com/paper/1804.00792/) (2018)
- [Confident Learning: Estimating Uncertainty in Dataset Labels](https://mlsanity.com/paper/1911.00068/) (2019)
- [Pervasive Label Errors in Test Sets Destabilize Machine Learning Benchmarks](https://mlsanity.com/paper/2103.14749/) (2021)
- [Data and its (dis)contents: A survey of dataset development and use in machine learning research](https://mlsanity.com/paper/2012.05345/) (2020)
- [Data-centric Artificial Intelligence: A Survey](https://mlsanity.com/paper/2303.10158/) (2023)
- [TabM: Advancing Tabular Deep Learning with Parameter-Efficient Ensembling](https://mlsanity.com/paper/2410.24210/) (2024)

## Abstract (arXiv)

Closed-loop discovery systems increasingly execute experiments and update decisions autonomously, turning record integrity into part of the experimental apparatus. We show that false-science induction arises when legitimate physical objects and measurements are paired incorrectly, driving neural surrogates to faithfully learn record-induced associations that do not correspond to the true object-outcome relationship while marginal data distributions remain unchanged. Across green fluorescent protein fitness and materials band-gap prediction loops, coherent paired misbinding systematically redirects experimental budgets toward low-performing basins, whereas same-volume random swaps have negligible effects. These observations identify error coherence, rather than raw error frequency, as the primary variable controlling this budget misallocation in the tested loops. The resulting binding identifiability boundary supports monitored-axis quarantines and feedback-conflict triage, which intercept over-concentrated proposals before execution and isolate the corrupted hypothesis axis.