# Anatomically Faithful Artifact Suppression in SENSE Accelerated Brain MRI

arXiv: https://arxiv.org/abs/2609.22390 · HTML: https://mlsanity.com/paper/2609.22390/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 9 of its 24 references that are in the map.
- First posted on arXiv 18 Sep 2026.

## Builds on (most cited first, 9 of 9)

- [The Unreasonable Effectiveness of Deep Features as a Perceptual Metric](https://mlsanity.com/paper/1801.03924/) (2018)
- [Squeeze-and-Excitation Networks](https://mlsanity.com/paper/1709.01507/) (2017)
- [CBAM: Convolutional Block Attention Module](https://mlsanity.com/paper/1807.06521/) (2018)
- [Improved Training of Wasserstein GANs](https://mlsanity.com/paper/1704.00028/) (2017)
- [A Deep Cascade of Convolutional Neural Networks for Dynamic MR Image Reconstruction](https://mlsanity.com/paper/1704.02422/) (2017)
- [Gradient Magnitude Similarity Deviation: A Highly Efficient Perceptual Image Quality Index](https://mlsanity.com/paper/1308.3052/) (2013)
- [FastSurfer -- A fast and accurate deep learning based neuroimaging pipeline](https://mlsanity.com/paper/1910.03866/) (2019)
- [Efficient and Accurate MRI Super-Resolution using a Generative Adversarial Network and 3D Multi-Level Densely Connected Network](https://mlsanity.com/paper/1803.01417/) (2018)
- [Swin Transformer for Fast MRI](https://mlsanity.com/paper/2201.03230/) (2022)

## Abstract (arXiv)

Background: Four-fold accelerated sensitivity encoding (SENSE4) can shorten brain MRI acquisition time but may amplify noise and result in residual aliasing artifacts after conventional reconstruction. Purpose: To evaluate whether an image-domain refinement framework can improve the quality of SENSE4 brain MRI while preserving anatomical information for quantitative measurements. Methods: In this prospective paired study, 80 participants underwent fully sampled and four-fold accelerated SENSE T1-weighted MRI. We developed an Anatomy-aware Residual Attention Network (ART-Net) to refine accelerated reconstructions through generalized self-attention and correlation-based residual artifact regularization. Participant-level splitting yielded training, validation, and independent test cohort (45/5/30 participants). The independent test cohort underwent quantitative, segmentation-based, and blinded radiologist assessments of image quality and anatomical preservation. Results: ART-Net demonstrated highly competitive reconstruction performance, achieving the highest peak signal-to-noise ratio (31.03 +/- 2.88 dB) and structural similarity index (0.963 +/- 0.022) among evaluated methods. It also demonstrated improved anatomical fidelity, with numerically highest Dice coefficients for medial temporal structures relevant to atrophy assessment (0.8824 +/- 0.0827) and whole-brain regions (0.8857 +/- 0.0885). Moreover, ART-Net improved gradient fidelity, regional contrast preservation, and radiologist-rated structural quality. Conclusion: ART-Net improved agreement between SENSE4 and fully sampled T1-weighted images in a single-center, held-out test cohort while maintaining segmentation-derived anatomical measurements. These findings suggest that ART-Net may support accelerated brain MRI by improving image fidelity and enabling reliable downstream anatomical analysis.