# PSMP-CLIP: Patch-Prompt SAM and Multi-Semantic Prompting for CLIP-Based Zero-Shot Anomaly Detection

arXiv: https://arxiv.org/abs/2609.16785 · HTML: https://mlsanity.com/paper/2609.16785/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 14 of its 25 references that are in the map.
- First posted on arXiv 15 Sep 2026.

## Builds on (most cited first, 14 of 14)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [SAM 2: Segment Anything in Images and Videos](https://mlsanity.com/paper/2408.00714/) (2024)
- [Kvasir-SEG: A Segmented Polyp Dataset](https://mlsanity.com/paper/1911.07069/) (2019)
- [SPot-the-Difference Self-Supervised Pre-training for Anomaly Detection and Segmentation](https://mlsanity.com/paper/2207.14315/) (2022)
- [WinCLIP: Zero-/Few-Shot Anomaly Classification and Segmentation](https://mlsanity.com/paper/2303.14814/) (2023)
- [Multiresolution Knowledge Distillation for Anomaly Detection](https://mlsanity.com/paper/2011.11108/) (2020)
- [VT-ADL: A Vision Transformer Network for Image Anomaly Detection and Localization](https://mlsanity.com/paper/2104.10036/) (2021)
- [AdaCLIP: Adapting CLIP with Hybrid Learnable Prompts for Zero-Shot Anomaly Detection](https://mlsanity.com/paper/2407.15795/) (2024)
- [AA-CLIP: Enhancing Zero-shot Anomaly Detection via Anomaly-Aware CLIP](https://mlsanity.com/paper/2503.06661/) (2025)
- [ClipSAM: CLIP and SAM Collaboration for Zero-Shot Anomaly Segmentation](https://mlsanity.com/paper/2401.12665/) (2024)
- [Bayesian Prompt Flow Learning for Zero-Shot Anomaly Detection](https://mlsanity.com/paper/2503.10080/) (2025)
- [MRAD: Zero-Shot Anomaly Detection with Memory-Driven Retrieval](https://mlsanity.com/paper/2602.00522/) (2026)
- [MSGCoOp: Multiple Semantic-Guided Context Optimization for Few-Shot Learning](https://mlsanity.com/paper/2507.21786/) (2025)

## Abstract (arXiv)

Zero-shot anomaly detection aims to localize anomalies without target-domain samples. Existing CLIP-based methods suffer from coarse anomaly maps and limited semantic prompts. We propose PSMP-CLIP, integrating patch-prompt SAM2 segmentation (PPSS) and multi-semantic guided prompt regularization (MSGPR). PPSS samples prompts directly from intermediate patch features, avoiding threshold drift and guiding SAM2 to produce precise masks. MSGPR uses multiple learnable prompts constrained by semantic anchors to preserve generalization. Experiments on 14 datasets show highly competitive performance, achieving the best pixel-level AUROC on MVTec AD, BTAD, DTD-Synthetic, CVC-ClinicDB, TN3K, Endo, and Kvasir.