# Decentralized Gossip Learning and Federated Averaging for Histopathology Image Classification

arXiv: https://arxiv.org/abs/2609.16448 · HTML: https://mlsanity.com/paper/2609.16448/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 21 of its 49 references that are in the map.
- First posted on arXiv 15 Sep 2026.

## Builds on (most cited first, 21 of 21)

- [Communication-Efficient Learning of Deep Networks from Decentralized Data](https://mlsanity.com/paper/1602.05629/) (2016)
- [Advances and Open Problems in Federated Learning](https://mlsanity.com/paper/1912.04977/) (2019)
- [Federated Optimization in Heterogeneous Networks](https://mlsanity.com/paper/1812.06127/) (2018)
- [Federated Learning: Challenges, Methods, and Future Directions](https://mlsanity.com/paper/1908.07873/) (2019)
- [Federated Learning: Strategies for Improving Communication Efficiency](https://mlsanity.com/paper/1610.05492/) (2016)
- [Towards Federated Learning at Scale: System Design](https://mlsanity.com/paper/1902.01046/) (2019)
- [The Future of Digital Health with Federated Learning](https://mlsanity.com/paper/2003.08119/) (2020)
- [Local SGD Converges Fast and Communicates Little](https://mlsanity.com/paper/1805.09767/) (2018)
- [Federated Learning with Differential Privacy: Algorithms and Performance Analysis](https://mlsanity.com/paper/1911.00222/) (2019)
- [Can Decentralized Algorithms Outperform Centralized Algorithms? A Case Study for Decentralized Parallel Stochastic Gradient Descent](https://mlsanity.com/paper/1705.09056/) (2017)
- [Federated Machine Learning: Concept and Applications](https://mlsanity.com/paper/1902.04885/) (2019)
- [Client Selection for Federated Learning with Heterogeneous Resources in Mobile Edge](https://mlsanity.com/paper/1804.08333/) (2018)
- [Federated Learning on Non-IID Data: A Survey](https://mlsanity.com/paper/2106.06843/) (2021)
- [Privacy-preserving Federated Brain Tumour Segmentation](https://mlsanity.com/paper/1910.00962/) (2019)
- [Demystifying Parallel and Distributed Deep Learning: An In-Depth Concurrency Analysis](https://mlsanity.com/paper/1802.09941/) (2018)
- [Privacy-Preserving Aggregation in Federated Learning: A Survey](https://mlsanity.com/paper/2203.17005/) (2022)
- [GossipGraD: Scalable Deep Learning using Gossip Communication based Asynchronous Gradient Descent](https://mlsanity.com/paper/1803.05880/) (2018)
- [A Survey on Model-heterogeneous Federated Learning: Problems, Methods, and Prospects](https://mlsanity.com/paper/2312.12091/) (2023)
- [SD-CNN: a Shallow-Deep CNN for Improved Breast Cancer Diagnosis](https://mlsanity.com/paper/1803.00663/) (2018)
- [Decentralized Personalization for Federated Medical Image Segmentation via Gossip Contrastive Mutual Learning](https://mlsanity.com/paper/2503.03883/) (2025)
- [Enhancing the Convergence of Federated Learning Aggregation Strategies with Limited Data](https://mlsanity.com/paper/2501.15949/) (2025)

## Abstract (arXiv)

Breast histopathology analysis increasingly relies on distributed learning because direct data pooling across institutions is often restricted by privacy, governance, and communication constraints. This study compares server-based Federated Averaging (FedAvg), fully decentralized gossip learning, and Hybrid Gossip-FedAvg for invasive ductal carcinoma (IDC) patch classification. Experiments used 277,524 color image patches with patient-disjoint training, validation, and test partitions and a workload-balanced, Dirichlet-guided allocation across six nodes. Ring, random degree-3, and fully connected gossip topologies were evaluated together with sensitivity analyses for statistical heterogeneity, mixing coefficient, learning rate, model drift, prediction disagreement, calibration, clinically motivated operating points, communication payload, and patient-level IDC burden, together with auxiliary backbone robustness analyses. In the principal alpha=0.3 experiment, Hybrid Gossip-FedAvg achieved a test area under the receiver operating characteristic curve (ROC-AUC) of 0.8811, closely followed by FedAvg at 0.8801 and fully connected gossip at 0.8751. Across three independent patient-level repetitions, FedAvg and Hybrid Gossip-FedAvg obtained the same mean ROC-AUC of 0.9082, with standard deviations of 0.0037 and 0.0043, respectively. Hybrid achieved the highest mean area under the precision-recall curve of 0.8240, whereas FedAvg produced the lowest mean Brier score of 0.1335. Denser gossip graphs improved discrimination but increased theoretical model payload, while ring gossip remained sensitive to learning rate and mixing strength. Overall, FedAvg provided the most consistently reliable server-based baseline, topology-aware gossip offered a viable decentralized alternative, and Hybrid Gossip-FedAvg provided a balanced compromise between peer-to-peer diffusion and periodic global coordination.