# Deep Learning-based Intelligent Diagnosis of Congenital Uterine Anomalies in 3D Ultrasound

arXiv: https://arxiv.org/abs/2609.15225 · HTML: https://mlsanity.com/paper/2609.15225/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 11 of its 30 references that are in the map.
- First posted on arXiv 14 Sep 2026.

## Builds on (most cited first, 11 of 11)

- [Segment Anything Model for Medical Images?](https://mlsanity.com/paper/2304.14660/) (2023)
- [Searching Collaborative Agents for Multi-plane Localization in 3D Ultrasound](https://mlsanity.com/paper/2007.15273/) (2020)
- [Fourier Test-time Adaptation with Multi-level Consistency for Robust Classification](https://mlsanity.com/paper/2306.02544/) (2023)
- [Agent with Warm Start and Adaptive Dynamic Termination for Plane Localization in 3D Ultrasound](https://mlsanity.com/paper/2103.14502/) (2021)
- [Searching Collaborative Agents for Multi-plane Localization in 3D Ultrasound](https://mlsanity.com/paper/2105.10626/) (2021)
- [Ctrl-GenAug: Controllable Generative Augmentation for Medical Sequence Classification](https://mlsanity.com/paper/2409.17091/) (2024)
- [Agent with Tangent-based Formulation and Anatomical Perception for Standard Plane Localization in 3D Ultrasound](https://mlsanity.com/paper/2207.00475/) (2022)
- [Flip Learning: Weakly Supervised Erase to Segment Nodules in Breast Ultrasound](https://mlsanity.com/paper/2503.20685/) (2025)
- [Artificial Intelligence for Detecting Fetal Orofacial Clefts and Advancing Medical Education](https://mlsanity.com/paper/2603.06522/) (2026)
- [Uncertainty-aware Diffusion and Reinforcement Learning for Joint Plane Localization and Anomaly Diagnosis in 3D Ultrasound](https://mlsanity.com/paper/2506.23538/) (2025)
- [MReg: A Novel Regression Model with MoE-based Video Feature Mining for Mitral Regurgitation Diagnosis](https://mlsanity.com/paper/2506.23648/) (2025)

## Abstract (arXiv)

Objective: To develop an intelligent framework, termed CUA-Net, for the automated classification of congenital uterine anomalies (CUA) without requiring coronal plane reconstruction, and to evaluate its clinical applicability. Methods: CUA-Net was built on 3D ResNet-18, equipped with a dynamic data resampling strategy to mitigate the data imbalance issue and a hard sample mining technique to fully learn from the difficult cases by loss adjustment. We further proposed the self-supervised reconstruction to comprehensively explore the volumes and the online data augmentation to refine the wrong predictions and enhance the model's generalization. We compared the CUA-Net with different deep-learning methods and junior/senior sonographers in the testing set. The evaluation metrics included accuracy, precision, recall, F1-score, micro-AUC, and macro-AUC. Results: The proposed CUA-Net exhibited satisfactory performance in both internal and external test sets. In the internal cohort, the model achieved accuracy of 93.88%, precision of 87.01%, recall of 95.92%, F1-score of 88.09%, and micro-AUC of 0.9982 and macro-AUC of 0.9997. In the external set, it maintained good performance with accuracy of 91.52%, precision of 83.27%, recall of 88.63%, F1-score of 81.49%, micro-AUC of 0.9945 and macro-AUC of 0.9990. Our CUA-Net outperformed the junior sonographers across all performance indicators and achieved performance comparable to that of the senior sonographers across most metrics. Conclusion: The CUA-Net demonstrates favorable accuracy and generalizability in classifying common CUA categories, while showing preliminary potential for recognizing less prevalent anomalies. These capabilities may help optimize clinical workflows and support more standardized diagnosis.