# Route, Don't Fix: Regime-Dependent Decoding Correction and a Trajectory-Gated Router for Reliable Clinical LLM Answer Selection

arXiv: https://arxiv.org/abs/2609.14825 · HTML: https://mlsanity.com/paper/2609.14825/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 16 of its 21 references that are in the map.
- First posted on arXiv 13 Sep 2026.

## Builds on (most cited first, 16 of 16)

- [Training language models to follow instructions with human feedback](https://mlsanity.com/paper/2203.02155/) (2022)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Qwen2.5 Technical Report](https://mlsanity.com/paper/2412.15115/) (2024)
- [TruthfulQA: Measuring How Models Mimic Human Falsehoods](https://mlsanity.com/paper/2109.07958/) (2021)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [Inference-Time Intervention: Eliciting Truthful Answers from a Language Model](https://mlsanity.com/paper/2306.03341/) (2023)
- [PubMedQA: A Dataset for Biomedical Research Question Answering](https://mlsanity.com/paper/1909.06146/) (2019)
- [SelfCheckGPT: Zero-Resource Black-Box Hallucination Detection for Generative Large Language Models](https://mlsanity.com/paper/2303.08896/) (2023)
- [RouteLLM: Learning to Route LLMs with Preference Data](https://mlsanity.com/paper/2406.18665/) (2024)
- [Eliciting Latent Predictions from Transformers with the Tuned Lens](https://mlsanity.com/paper/2303.08112/) (2023)
- [Contrastive Decoding: Open-ended Text Generation as Optimization](https://mlsanity.com/paper/2210.15097/) (2022)
- [DoLa: Decoding by Contrasting Layers Improves Factuality in Large Language Models](https://mlsanity.com/paper/2309.03883/) (2023)
- [Chain-of-Verification Reduces Hallucination in Large Language Models](https://mlsanity.com/paper/2309.11495/) (2023)
- [MedHallu: A Comprehensive Benchmark for Detecting Medical Hallucinations in Large Language Models](https://mlsanity.com/paper/2502.14302/) (2025)
- [SLED: Self Logits Evolution Decoding for Improving Factuality in Large Language Models](https://mlsanity.com/paper/2411.02433/) (2024)
- [DeLTa: A Decoding Strategy based on Logit Trajectory Prediction Improves Factuality and Reasoning Ability](https://mlsanity.com/paper/2503.02343/) (2025)

## Abstract (arXiv)

Large language models (LLMs) are often deemed unsafe for clinical question answering because of their tendency to hallucinate. Retrieval augmentation, fine-tuning, and external verifiers require new infrastructure that clinical governance must approve and may add latency or extra model calls. Inference-time correction uses the model's internal logit signals, but a fixed transformation need not suit every question. A corrector that improves accuracy by about ten percentage points on a truthfulness stress test yields negligible gains on clinical multiple-choice benchmarks, where instruction tuning concentrates output probability on one answer and leaves low terminal entropy. We introduce ALTAS, which reads terminal entropy and late-layer linearity (R2) from one forward pass to choose per question between greedy decoding and late-layer trajectory correction. No classifier, probe, or head is trained; the router operates on candidate-answer logits and adds 6.5% latency overhead. Applied to every question, the correction improves TruthfulQA over greedy at 3B and 8B by 11.4 and 10.0 percentage points, respectively (p<10-10). Gated per question, ALTAS retains gains of 8.3 to 9.5 percentage points while keeping MedQA, PubMedQA, and MedHallu within a one-percentage-point do-no-harm band, with no statistically significant differences from greedy. The method passes verification sweeps over frozen thresholds, the scoring rule, and the domain label.
