# MedRoundsQA: A Persona and Difficulty Aware Evaluation for Multi-Turn Medical Consultations

arXiv: https://arxiv.org/abs/2609.12851 · HTML: https://mlsanity.com/paper/2609.12851/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 22 of its 46 references that are in the map.
- First posted on arXiv 11 Sep 2026.

## Builds on (most cited first, 22 of 22)

- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [Large Language Models Encode Clinical Knowledge](https://mlsanity.com/paper/2212.13138/) (2022)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [PubMedQA: A Dataset for Biomedical Research Question Answering](https://mlsanity.com/paper/1909.06146/) (2019)
- [GLM-5: from Vibe Coding to Agentic Engineering](https://mlsanity.com/paper/2602.15763/) (2026)
- [ChatDoctor: A Medical Chat Model Fine-Tuned on a Large Language Model Meta-AI (LLaMA) Using Medical Domain Knowledge](https://mlsanity.com/paper/2303.14070/) (2023)
- [HuatuoGPT-o1, Towards Medical Complex Reasoning with LLMs](https://mlsanity.com/paper/2412.18925/) (2024)
- [AgentClinic: a multimodal agent benchmark to evaluate AI in simulated clinical environments](https://mlsanity.com/paper/2405.07960/) (2024)
- [When More is Less: Understanding Chain-of-Thought Length in LLMs](https://mlsanity.com/paper/2502.07266/) (2025)
- [MedDialog: Two Large-scale Medical Dialogue Datasets](https://mlsanity.com/paper/2004.03329/) (2020)
- [MediQ: Question-Asking LLMs and a Benchmark for Reliable Interactive Clinical Reasoning](https://mlsanity.com/paper/2406.00922/) (2024)
- [AI Hospital: Benchmarking Large Language Models in a Multi-agent Medical Interaction Simulator](https://mlsanity.com/paper/2402.09742/) (2024)
- [Diagnostic Reasoning Prompts Reveal the Potential for Large Language Model Interpretability in Medicine](https://mlsanity.com/paper/2308.06834/) (2023)
- [Baichuan-M2: Scaling Medical Capability with Large Verifier System](https://mlsanity.com/paper/2509.02208/) (2025)
- [MedDG: An Entity-Centric Medical Consultation Dataset for Entity-Aware Medical Dialogue Generation](https://mlsanity.com/paper/2010.07497/) (2020)
- [A Benchmark for Automatic Medical Consultation System: Frameworks, Tasks and Datasets](https://mlsanity.com/paper/2204.08997/) (2022)
- [Self-Evolving Multi-Agent Simulations for Realistic Clinical Interactions](https://mlsanity.com/paper/2503.22678/) (2025)
- [Ask Patients with Patience: Enabling LLMs for Human-Centric Medical Dialogue with Grounded Reasoning](https://mlsanity.com/paper/2502.07143/) (2025)
- [3MDBench: Medical Multimodal Multi-agent Dialogue Benchmark](https://mlsanity.com/paper/2504.13861/) (2025)
- [Shallow Robustness, Deep Vulnerabilities: Multi-Turn Evaluation of Medical LLMs](https://mlsanity.com/paper/2510.12255/) (2025)
- [MedMT-Bench: Can LLMs Memorize and Understand Long Multi-Turn Conversations in Medical Scenarios?](https://mlsanity.com/paper/2603.23519/) (2026)
- [Can Model Uncertainty Function as a Proxy for Multiple-Choice Question Item Difficulty?](https://mlsanity.com/paper/2407.05327/) (2024)

## Abstract (arXiv)

Medical benchmarks are dominated by single-turn, multiple-choice clinical cases that poorly reflect real consultations. Practically, clinicians elicit evidence interactively and patient communication varies widely. We introduce MedRoundsQA, a multi-turn diagnostic benchmark derived from 1,387 board-exam cases across 17 specialties. Each case is converted into a structured 24-slot clinical record, and then instantiated as controlled doctor-patient dual-agent dialogues under varying patient personas, with the underlying clinical content held fixed. We further classify cases by difficulty using model-based uncertainty to enable easy-to-hard analysis. Evaluations of fifteen LLM doctor agents show that (i) moving from a single-turn diagnosis on the standardized records to multi-turn consultations causes large degradations of roughly 13-39 points; (ii) more turns reliably improves question relevance, but diagnostic accuracy exhibits diminishing returns and typically plateaus after 6-12 turns; and (iii) patient persona differences can shift diagnosis accuracy by about 7-8 points (lowest to highest education), highlighting equity risks that single-turn benchmarks miss.