# S3-Bench: Evaluating Speech Interaction Models as Scientific Voice Assistants

arXiv: https://arxiv.org/abs/2609.09852 · HTML: https://mlsanity.com/paper/2609.09852/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in MLLM training and visual instruction tuning, one of 16 directions in Multimodal LLMs / vision-language models.
- Builds on 59 of its 73 references that are in the map.
- First posted on arXiv 9 Sep 2026.

## Placed in

- Multimodal LLMs / vision-language models / [MLLM training and visual instruction tuning](https://mlsanity.com/mllm/mllm-training-and-visual-instruction-tuning/)

## Builds on (most cited first, 30 of 59)

- [Qwen3 Technical Report](https://mlsanity.com/paper/2505.09388/) (2025)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [Robust Speech Recognition via Large-Scale Weak Supervision](https://mlsanity.com/paper/2212.04356/) (2022)
- [GPQA: A Graduate-Level Google-Proof Q&A Benchmark](https://mlsanity.com/paper/2311.12022/) (2023)
- [MMMU: A Massive Multi-discipline Multimodal Understanding and Reasoning Benchmark for Expert AGI](https://mlsanity.com/paper/2311.16502/) (2023)
- [Learn to Explain: Multimodal Reasoning via Thought Chains for Science Question Answering](https://mlsanity.com/paper/2209.09513/) (2022)
- [MMLU-Pro: A More Robust and Challenging Multi-Task Language Understanding Benchmark](https://mlsanity.com/paper/2406.01574/) (2024)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [PubMedQA: A Dataset for Biomedical Research Question Answering](https://mlsanity.com/paper/1909.06146/) (2019)
- [HuggingGPT: Solving AI Tasks with ChatGPT and its Friends in Hugging Face](https://mlsanity.com/paper/2303.17580/) (2023)
- [Large Language Models](https://mlsanity.com/paper/2307.05782/) (2023)
- [Qwen2.5-Omni Technical Report](https://mlsanity.com/paper/2503.20215/) (2025)
- [C-Eval: A Multi-Level Multi-Discipline Chinese Evaluation Suite for Foundation Models](https://mlsanity.com/paper/2305.08322/) (2023)
- [Moshi: a speech-text foundation model for real-time dialogue](https://mlsanity.com/paper/2410.00037/) (2024)
- [MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answering](https://mlsanity.com/paper/2203.14371/) (2022)
- [MMMU-Pro: A More Robust Multi-discipline Multimodal Understanding Benchmark](https://mlsanity.com/paper/2409.02813/) (2024)
- [Qwen3-Omni Technical Report](https://mlsanity.com/paper/2509.17765/) (2025)
- [GigaSpeech: An Evolving, Multi-domain ASR Corpus with 10,000 Hours of Transcribed Audio](https://mlsanity.com/paper/2106.06909/) (2021)
- [Seed-TTS: A Family of High-Quality Versatile Speech Generation Models](https://mlsanity.com/paper/2406.02430/) (2024)
- [AudioGPT: Understanding and Generating Speech, Music, Sound, and Talking Head](https://mlsanity.com/paper/2304.12995/) (2023)
- [GLM-4-Voice: Towards Intelligent and Human-Like End-to-End Spoken Chatbot](https://mlsanity.com/paper/2412.02612/) (2024)
- [MedXpertQA: Benchmarking Expert-Level Medical Reasoning and Understanding](https://mlsanity.com/paper/2501.18362/) (2025)
- [Kimi-Audio Technical Report](https://mlsanity.com/paper/2504.18425/) (2025)
- [AIR-Bench: Benchmarking Large Audio-Language Models via Generative Comprehension](https://mlsanity.com/paper/2402.07729/) (2024)
- [Mini-Omni: Language Models Can Hear, Talk While Thinking in Streaming](https://mlsanity.com/paper/2408.16725/) (2024)
- [Qwen3.5-Omni Technical Report](https://mlsanity.com/paper/2604.15804/) (2026)
- [LLaMA-Omni: Seamless Speech Interaction with Large Language Models](https://mlsanity.com/paper/2409.06666/) (2024)
- [LAB-Bench: Measuring Capabilities of Language Models for Biology Research](https://mlsanity.com/paper/2407.10362/) (2024)
- [CosyVoice 3: Towards In-the-wild Speech Generation via Scaling-up and Post-training](https://mlsanity.com/paper/2505.17589/) (2025)
- [Freeze-Omni: A Smart and Low Latency Speech-to-speech Dialogue Model with Frozen LLM](https://mlsanity.com/paper/2411.00774/) (2024)

## Abstract (arXiv)

The advance of multimodal large language models (MLLMs) has fundamentally reshaped the paradigm of human-computer interaction, especially speech interaction models capable of seamless conversations. Despite remarkable performance as general voice assistants, their performance in specialized domains remains underexplored, particularly in scientific areas. Scientific interactions introduce formidable challenges, involving rare technical terminology, spoken norms of abbreviations, and the natural verbalization of symbolic special expressions. In this paper, we introduce S3-Bench, a systematic evaluation framework covering 10 major disciplines, consisting of a Knowledge set for speech question-answering and a Dialogue set for multi-turn progressive interactions with simulated user agents. By decomposing a complete atomic turn into stages of speech recognition, perception, knowledge utilization with reasoning, and response pronunciation, we systematically characterize the common challenges and performance tradeoffs of existing approaches. Furthermore, experiments on multi-turn interactions reveal persistent limitations in user adaptation and the generation of accurate, comprehensive, and efficient responses.