# MMTClinic: Multimodal, Multilingual Time Series Question Answering and Reasoning Benchmark for Clinical Domain

arXiv: https://arxiv.org/abs/2609.04842 · HTML: https://mlsanity.com/paper/2609.04842/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning.
- Builds on 36 of its 51 references that are in the map.
- First posted on arXiv 4 Sep 2026.

## Placed in

- LLM reasoning / [Clinical and biomedical applications](https://mlsanity.com/lr/clinical-and-biomedical-applications/)

## Builds on (most cited first, 30 of 36)

- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
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- [Gemma 3 Technical Report](https://mlsanity.com/paper/2503.19786/) (2025)
- [Qwen2.5-Coder Technical Report](https://mlsanity.com/paper/2409.12186/) (2024)
- [MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answering](https://mlsanity.com/paper/2203.14371/) (2022)
- [ProcessBench: Identifying Process Errors in Mathematical Reasoning](https://mlsanity.com/paper/2412.06559/) (2024)
- [Towards Generalist Biomedical AI](https://mlsanity.com/paper/2307.14334/) (2023)
- [WeatherBench: A benchmark dataset for data-driven weather forecasting](https://mlsanity.com/paper/2002.00469/) (2020)
- [Can large language models reason about medical questions?](https://mlsanity.com/paper/2207.08143/) (2022)
- [MediQ: Question-Asking LLMs and a Benchmark for Reliable Interactive Clinical Reasoning](https://mlsanity.com/paper/2406.00922/) (2024)
- [MedFuse: Multi-modal fusion with clinical time-series data and chest X-ray images](https://mlsanity.com/paper/2207.07027/) (2022)
- [ECG-QA: A Comprehensive Question Answering Dataset Combined With Electrocardiogram](https://mlsanity.com/paper/2306.15681/) (2023)
- [EHRXQA: A Multi-Modal Question Answering Dataset for Electronic Health Records with Chest X-ray Images](https://mlsanity.com/paper/2310.18652/) (2023)
- [CLIPSyntel: CLIP and LLM Synergy for Multimodal Question Summarization in Healthcare](https://mlsanity.com/paper/2312.11541/) (2023)
- [MedExpQA: Multilingual Benchmarking of Large Language Models for Medical Question Answering](https://mlsanity.com/paper/2404.05590/) (2024)
- [TIMER: Temporal Instruction Modeling and Evaluation for Longitudinal Clinical Records](https://mlsanity.com/paper/2503.04176/) (2025)
- [A Survey of Multilingual Reasoning in Language Models](https://mlsanity.com/paper/2502.09457/) (2025)
- [Limitations of Large Language Models in Clinical Problem-Solving Arising from Inflexible Reasoning](https://mlsanity.com/paper/2502.04381/) (2025)
- [AM-Thinking-v1: Advancing the Frontier of Reasoning at 32B Scale](https://mlsanity.com/paper/2505.08311/) (2025)
- [INDIC QA BENCHMARK: A Multilingual Benchmark to Evaluate Question Answering capability of LLMs for Indic Languages](https://mlsanity.com/paper/2407.13522/) (2024)
- [NurViD: A Large Expert-Level Video Database for Nursing Procedure Activity Understanding](https://mlsanity.com/paper/2310.13347/) (2023)
- [MedSumm: A Multimodal Approach to Summarizing Code-Mixed Hindi-English Clinical Queries](https://mlsanity.com/paper/2401.01596/) (2024)
- [MedTsLLM: Leveraging LLMs for Multimodal Medical Time Series Analysis](https://mlsanity.com/paper/2408.07773/) (2024)
- [Q-Heart: ECG Question Answering via Knowledge-Informed Multimodal LLMs](https://mlsanity.com/paper/2505.06296/) (2025)
- [Temporal Consistency for LLM Reasoning Process Error Identification](https://mlsanity.com/paper/2503.14495/) (2025)
- [Efficient LLaMA-3.2-Vision by Trimming Cross-attended Visual Features](https://mlsanity.com/paper/2504.00557/) (2025)
- [CLINIC: Evaluating Multilingual Trustworthiness in Language Models for Healthcare](https://mlsanity.com/paper/2512.11437/) (2025)

## Abstract (arXiv)

Time-series data in clinical settings is crucial for capturing dynamic changes in a patient's health over time, enabling timely diagnosis, personalized treatment, and early detection of critical events. However, the development of clinically reliable and linguistically inclusive medical AI systems remains a significant challenge, primarily due to the lack of multimodal, multilingual, and time-series-grounded benchmarks that reflect the complexity of real-world clinical scenarios. To fill this gap, we present MMTClinic, a benchmark designed to evaluate large language models (LLMs) on complex reasoning and question-answering tasks involving clinical time-series. MMTClinic combines text, medical images, and multivariate physiological signals and includes 30,000 QA pairs (15,000 multiple choice questions (MCQs) and 15,000 open-ended questions) across five languages: English, Hindi, Bengali, Marathi, and Tamil. These questions cover three important clinical tasks---mortality prediction, heart rate forecasting, and SOFA score estimation. We evaluate 13 state-of-the-art LLMs in zero-shot, few-shot, and chain-of-thought settings. Our evaluation reveals notable differences in model performance across tasks, languages, and modalities, highlighting current limitations in clinical reasoning capabilities. MMTClinic provides a valuable resource for advancing multilingual, multimodal, and time-series-aware medical AI research. The dataset will be made publicly available on successful acceptance of the work.