# Paper Pilot: A Human-in-the-Loop Expert System for Evidence-Traceable Scientific Manuscript Generation in Applied Sciences

arXiv: https://arxiv.org/abs/2608.28596 · HTML: https://mlsanity.com/paper/2608.28596/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 12 of its 15 references that are in the map.
- First posted on arXiv 17 Jun 2026.

## Builds on (most cited first, 12 of 12)

- [The AI Scientist: Towards Fully Automated Open-Ended Scientific Discovery](https://mlsanity.com/paper/2408.06292/) (2024)
- [Agent Laboratory: Using LLM Agents as Research Assistants](https://mlsanity.com/paper/2501.04227/) (2025)
- [The AI Scientist-v2: Workshop-Level Automated Scientific Discovery via Agentic Tree Search](https://mlsanity.com/paper/2504.08066/) (2025)
- [CycleResearcher: Improving Automated Research via Automated Review](https://mlsanity.com/paper/2411.00816/) (2024)
- [Agentic AI for Scientific Discovery: A Survey of Progress, Challenges, and Future Directions](https://mlsanity.com/paper/2503.08979/) (2025)
- [AgentRxiv: Towards Collaborative Autonomous Research](https://mlsanity.com/paper/2503.18102/) (2025)
- [InternAgent: When Agent Becomes the Scientist -- Building Closed-Loop System from Hypothesis to Verification](https://mlsanity.com/paper/2505.16938/) (2025)
- [OmniScientist: Toward a Co-evolving Ecosystem of Human and AI Scientists](https://mlsanity.com/paper/2511.16931/) (2025)
- [PaperOrchestra: A Multi-Agent Framework for Automated AI Research Paper Writing](https://mlsanity.com/paper/2604.05018/) (2026)
- [AutoSurvey2: Empowering Researchers with Next Level Automated Literature Surveys](https://mlsanity.com/paper/2510.26012/) (2025)
- [ARISE: Agentic Rubric-Guided Iterative Survey Engine for Automated Scholarly Paper Generation](https://mlsanity.com/paper/2511.17689/) (2025)
- [Collaborative Agent Reasoning Engineering (CARE): A Three-Party Design Methodology for Systematically Engineering AI Agents with Subject Matter Experts, Developers, and Helper Agents](https://mlsanity.com/paper/2604.28043/) (2026)

## Abstract (arXiv)

Large language model (LLM) agents are increasingly embedded in scientific workflows for literature analysis, drafting, and review. Existing systems advance autonomous discovery and manuscript generation, but do not resolve the governance problem that arises when ideas, methods, results, and claims propagate through AI-assisted workflows without mandatory human approval or artifact-level traceability. This paper proposes Paper Pilot, a human-in-the-loop expert system for evidence-traceable scientific manuscript generation in applied sciences. It adapts the Collaborative Agent Reasoning Engineering (CARE) methodology to manuscript development through manuscript-owner approval gates, explicit no-pass criteria, claim classification, audit logging, advisory LLM review, and evidence-locked revision control. The framework defines eight approval gates across the idea-to-claim pipeline and distinguishes literature-grounded from artifact-grounded claims, requiring reported numbers and interpretations to remain traceable to approved evidence; its system prompt is openly released for deployment in ChatGPT, Gemini, Claude, or institutional LLM environments. As a first empirical validation, we evaluate the citation-grounding layer with a controlled, mechanically scored benchmark (two commercial LLMs, real arXiv papers, no LLM judge): under coverage pressure ungated drafters fabricated up to 25% of their citations and never flagged an evidence gap, whereas the same models under Paper Pilot's evidence-locked rules produced zero fabricated citations and surfaced the planted gaps as explicit placeholders. Preliminary results for result grounding, revision, and adversarial robustness point the same way; full evaluation is left to future work. Paper Pilot positions LLM-assisted writing as a controlled human-AI decision-support process rather than a fully autonomous authorship pipeline.