# Adaptive Memory and Reflection Multi-Agent System for Medical Question Answering

arXiv: https://arxiv.org/abs/2608.19029 · HTML: https://mlsanity.com/paper/2608.19029/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 14 of its 30 references that are in the map.
- First posted on arXiv 19 Aug 2026.

## Builds on (most cited first, 14 of 14)

- [Improving Factuality and Reasoning in Language Models through Multiagent Debate](https://mlsanity.com/paper/2305.14325/) (2023)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answering](https://mlsanity.com/paper/2203.14371/) (2022)
- [MedAgents: Large Language Models as Collaborators for Zero-shot Medical Reasoning](https://mlsanity.com/paper/2311.10537/) (2023)
- [ReConcile: Round-Table Conference Improves Reasoning via Consensus among Diverse LLMs](https://mlsanity.com/paper/2309.13007/) (2023)
- [Agentic Retrieval-Augmented Generation: A Survey on Agentic RAG](https://mlsanity.com/paper/2501.09136/) (2025)
- [MDAgents: An Adaptive Collaboration of LLMs for Medical Decision-Making](https://mlsanity.com/paper/2404.15155/) (2024)
- [Biomedical Question Answering: A Survey of Approaches and Challenges](https://mlsanity.com/paper/2102.05281/) (2021)
- [Rationale-Guided Retrieval Augmented Generation for Medical Question Answering](https://mlsanity.com/paper/2411.00300/) (2024)
- [KG4Diagnosis: A Hierarchical Multi-Agent LLM Framework with Knowledge Graph Enhancement for Medical Diagnosis](https://mlsanity.com/paper/2412.16833/) (2024)
- [Medchain: Bridging the Gap Between LLM Agents and Clinical Practice with Interactive Sequence](https://mlsanity.com/paper/2412.01605/) (2024)
- [Large Language Models and User Trust: Consequence of Self-Referential Learning Loop and the Deskilling of Healthcare Professionals](https://mlsanity.com/paper/2403.14691/) (2024)
- [Towards Reliable and Fluent Large Language Models: Incorporating Feedback Learning Loops in QA Systems](https://mlsanity.com/paper/2309.06384/) (2023)
- [Exploring Collaborative GenAI Agents in Synchronous Group Settings: Eliciting Team Perceptions and Design Considerations for the Future of Work](https://mlsanity.com/paper/2504.14779/) (2025)

## Abstract (arXiv)

Accurate and responsible medical question answering (QA) is important in healthcare, where complex cases require factual knowledge and nuanced reasoning. Existing medical QA systems, typically based on single-agent architectures and static retrieval, often lack adaptability, persistent memory, and structured decision-making. This work introduces an adaptive memory and reflection (AMR) agentic system, a multi-agent framework in which specialized agents use dedicated memory and reflection-based feedback to retrieve relevant prior cases and improve subsequent reasoning. Complexity assessment routes questions through solo, collaborative, or escalated workflows, while consensus and ethical overseer modules support reasoning consolidation and output review. Evaluation on MedQA and MedMCQA demonstrates strong performance compared with several baselines. Ablation studies show that combining agent-specific memory, reflection, and external retrieval yields the strongest performance. These findings highlight the potential of structured memory and feedback for developing more trustworthy medical agents. The source code is publicly available at https://github.com/mm-air/AMR-Agent.