# Delta2Gamma: Band-Wise Adaptive Contrastive Learning of EEG for Alzheimer's Disease Detection

arXiv: https://arxiv.org/abs/2608.17231 · HTML: https://mlsanity.com/paper/2608.17231/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 9 of its 46 references that are in the map.
- First posted on arXiv 18 Aug 2026.

## Builds on (most cited first, 9 of 9)

- [A Simple Framework for Contrastive Learning of Visual Representations](https://mlsanity.com/paper/2002.05709/) (2020)
- [Batch Normalization: Accelerating Deep Network Training by Reducing Internal Covariate Shift](https://mlsanity.com/paper/1502.03167/) (2015)
- [An Empirical Evaluation of Generic Convolutional and Recurrent Networks for Sequence Modeling](https://mlsanity.com/paper/1803.01271/) (2018)
- [EEGNet: A Compact Convolutional Network for EEG-based Brain-Computer Interfaces](https://mlsanity.com/paper/1611.08024/) (2016)
- [Large Brain Model for Learning Generic Representations with Tremendous EEG Data in BCI](https://mlsanity.com/paper/2405.18765/) (2024)
- [FBCNet: A Multi-view Convolutional Neural Network for Brain-Computer Interface](https://mlsanity.com/paper/2104.01233/) (2021)
- [S-JEPA: towards seamless cross-dataset transfer through dynamic spatial attention](https://mlsanity.com/paper/2403.11772/) (2024)
- [Adaptive Multi-head Contrastive Learning](https://mlsanity.com/paper/2310.05615/) (2023)
- [Reasoning-Based Approach with Chain-of-Thought for Alzheimer's Detection Using Speech and Large Language Models](https://mlsanity.com/paper/2506.01683/) (2025)

## Abstract (arXiv)

Low-cost, scalable screening for dementia remains an open problem. Imaging-based diagnosis is costly and hard to deploy widely. Electroencephalography (EEG) is portable and inexpensive, but its recordings are noisy, vary widely across subjects, and carry few clinical labels. We tackle this with Delta2Gamma, a self-supervised framework that learns EEG representations from unlabeled data by contrasting augmented views of each signal. Rather than treat EEG as a single stream, Delta2Gamma decomposes every recording into the five canonical neural rhythms (delta, theta, alpha, beta, gamma). Each band gets its own encoder and projection head. Each also gets a temperature that is predicted adaptively during contrastive training, so bands with different signal statistics are balanced automatically. On the ADFTD cohort under a strict leave-one-subject-out protocol, Delta2Gamma separates Alzheimer's disease from cognitively normal controls with 92.4% accuracy. This exceeds both supervised backbones and recent dedicated EEG methods.