# RadFusion: Towards Threshold-Controllable Radiology Report Generation

arXiv: https://arxiv.org/abs/2608.10505 · HTML: https://mlsanity.com/paper/2608.10505/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 37 of its 49 references that are in the map.
- First posted on arXiv 11 Aug 2026.

## Builds on (most cited first, 30 of 37)

- [Classifier-Free Diffusion Guidance](https://mlsanity.com/paper/2207.12598/) (2022)
- [Self-Consistency Improves Chain of Thought Reasoning in Language Models](https://mlsanity.com/paper/2203.11171/) (2022)
- [On Calibration of Modern Neural Networks](https://mlsanity.com/paper/1706.04599/) (2017)
- [Language Models (Mostly) Know What They Know](https://mlsanity.com/paper/2207.05221/) (2022)
- [CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison](https://mlsanity.com/paper/1901.07031/) (2019)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [DeepSeek-V4: Towards Highly Efficient Million-Token Context Intelligence](https://mlsanity.com/paper/2606.19348/) (2026)
- [OpenAI GPT-5 System Card](https://mlsanity.com/paper/2601.03267/) (2025)
- [Can LLMs Express Their Uncertainty? An Empirical Evaluation of Confidence Elicitation in LLMs](https://mlsanity.com/paper/2306.13063/) (2023)
- [Plug and Play Language Models: A Simple Approach to Controlled Text Generation](https://mlsanity.com/paper/1912.02164/) (2019)
- [PathVQA: 30000+ Questions for Medical Visual Question Answering](https://mlsanity.com/paper/2003.10286/) (2020)
- [SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answering](https://mlsanity.com/paper/2102.09542/) (2021)
- [MedGemma Technical Report](https://mlsanity.com/paper/2507.05201/) (2025)
- [Med-Flamingo: a Multimodal Medical Few-shot Learner](https://mlsanity.com/paper/2307.15189/) (2023)
- [FUDGE: Controlled Text Generation With Future Discriminators](https://mlsanity.com/paper/2104.05218/) (2021)
- [Generating Radiology Reports via Memory-driven Transformer](https://mlsanity.com/paper/2010.16056/) (2020)
- [Towards Generalist Biomedical AI](https://mlsanity.com/paper/2307.14334/) (2023)
- [Cross-modal Memory Networks for Radiology Report Generation](https://mlsanity.com/paper/2204.13258/) (2022)
- [DaViT: Dual Attention Vision Transformers](https://mlsanity.com/paper/2204.03645/) (2022)
- [When Radiology Report Generation Meets Knowledge Graph](https://mlsanity.com/paper/2002.08277/) (2020)
- [MAIRA-2: Grounded Radiology Report Generation](https://mlsanity.com/paper/2406.04449/) (2024)
- [Interactive and Explainable Region-guided Radiology Report Generation](https://mlsanity.com/paper/2304.08295/) (2023)
- [Improving Chest X-Ray Report Generation by Leveraging Warm Starting](https://mlsanity.com/paper/2201.09405/) (2022)
- [PromptMRG: Diagnosis-Driven Prompts for Medical Report Generation](https://mlsanity.com/paper/2308.12604/) (2023)
- [MAIRA-1: A specialised large multimodal model for radiology report generation](https://mlsanity.com/paper/2311.13668/) (2023)
- [ConfTuner: Training Large Language Models to Express Their Confidence Verbally](https://mlsanity.com/paper/2508.18847/) (2025)
- [MedVersa: A Generalist Foundation Model for Medical Image Interpretation](https://mlsanity.com/paper/2405.07988/) (2024)
- [When Does Optimizing a Proper Loss Yield Calibration?](https://mlsanity.com/paper/2305.18764/) (2023)
- [Libra: Leveraging Temporal Images for Biomedical Radiology Analysis](https://mlsanity.com/paper/2411.19378/) (2024)
- [VisualCheXbert: Addressing the Discrepancy Between Radiology Report Labels and Image Labels](https://mlsanity.com/paper/2102.11467/) (2021)

## Abstract (arXiv)

Automated radiology report generation is advancing rapidly in response to the shortage of radiologists, yet unlike a perception model, existing generation models offer no control over the sensitivity-specificity trade-off of their diagnostic content. Such control is essential because clinical scenarios diverge: emergency triage prioritizes sensitivity to reduce missed findings, whereas confirmatory interpretation emphasizes specificity to limit unnecessary interventions. A single fixed report can neither adapt to these scenarios nor support the ROC-based validation widely expected for regulatory clearance. We introduce RadFusion, a framework that equips report generation with threshold controllability. Our method fuses a multi-label classifier, which provides per-disease confidence scores, with a VQA-based report generator, which describes medical findings in detail; an LLM then rewrites the report so that its stated diagnoses follow the classifier's decisions at the selected threshold while staying grounded in the generator's descriptions. On MIMIC-CXR, the performance of RadFusion conforms to the classifier's ROC curve: sweeping the threshold and mapping the reports back to class labels reproduces the classifier's validated ROC performance. This conformance makes generated reports quantitatively evaluable through ROC analysis, strengthening the case for regulatory clearance, and enables operating-point selection that matches report behavior to clinical context. Moreover, combining the two model types improves diagnostic accuracy over uncontrolled generation: sensitivity increases by 6.9% at matched specificity, and specificity by 20.7% at matched sensitivity. These results show that RadFusion makes report generation clinically adaptable, quantitatively verifiable, and diagnostically more reliable.
