# Efficient Noise Context-Aware Representation for Low-Dose CT Denoising

arXiv: https://arxiv.org/abs/2608.10343 · HTML: https://mlsanity.com/paper/2608.10343/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 11 of its 25 references that are in the map.
- First posted on arXiv 11 Aug 2026.

## Builds on (most cited first, 11 of 11)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Perceptual Losses for Real-Time Style Transfer and Super-Resolution](https://mlsanity.com/paper/1603.08155/) (2016)
- [Beyond a Gaussian Denoiser: Residual Learning of Deep CNN for Image Denoising](https://mlsanity.com/paper/1608.03981/) (2016)
- [Uformer: A General U-Shaped Transformer for Image Restoration](https://mlsanity.com/paper/2106.03106/) (2021)
- [Simple Baselines for Image Restoration](https://mlsanity.com/paper/2204.04676/) (2022)
- [Noise2Noise: Learning Image Restoration without Clean Data](https://mlsanity.com/paper/1803.04189/) (2018)
- [Benchmarking Denoising Algorithms with Real Photographs](https://mlsanity.com/paper/1707.01313/) (2017)
- [Run, Don't Walk: Chasing Higher FLOPS for Faster Neural Networks](https://mlsanity.com/paper/2303.03667/) (2023)
- [CT Super-resolution GAN Constrained by the Identical, Residual, and Cycle Learning Ensemble(GAN-CIRCLE)](https://mlsanity.com/paper/1808.04256/) (2018)
- [Differentiable Forward Projector for X-ray Computed Tomography](https://mlsanity.com/paper/2307.05801/) (2023)
- [sFRC for assessing hallucinations in medical image restoration](https://mlsanity.com/paper/2603.04673/) (2026)

## Abstract (arXiv)

While deep learning-based denoising has become widely adopted in low-dose CT, conventional models use generic architectures designed for natural images, failing to account for non-stationary and spatially correlated CT noise characteristics. To address this, we propose an Efficient Noise COntext-aware REpresentation (ENCORE) framework that explicitly leverages CT noise characteristics and anatomical features. First, we reformulate the noise synthesis procedure based on a realistic noise distribution beyond the conventional Gaussian approximation, establishing a rigorous foundation for training pair generation. Next, we extract local noise power and correlation contexts to guide the denoising process. To fully leverage the potential of noise context, we propose a FlyingConv module, which adaptively changes convolution weights for each local image region. Notably, our approach demonstrates substantial gains in both denoising quality and computational efficiency. Furthermore, manipulating the intensity of the noise context maps at inference time enables zero-shot conditional denoising, allowing for dynamic control over the output image texture. The entire pipeline is available at https://github.com/minwoo-yu/ENCORE.git