# Boosting Generalizable Depth Estimation in Endoscopy by Mixture of Lightweight Experts and Intrinsic Image Alignment

arXiv: https://arxiv.org/abs/2608.00415 · HTML: https://mlsanity.com/paper/2608.00415/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 11 of its 19 references that are in the map.
- First posted on arXiv 1 Aug 2026.

## Builds on (most cited first, 11 of 11)

- [Depth Anything V2](https://mlsanity.com/paper/2406.09414/) (2024)
- [Depth Anything: Unleashing the Power of Large-Scale Unlabeled Data](https://mlsanity.com/paper/2401.10891/) (2024)
- [MonoViT: Self-Supervised Monocular Depth Estimation with a Vision Transformer](https://mlsanity.com/paper/2208.03543/) (2022)
- [Stereo Correspondence and Reconstruction of Endoscopic Data Challenge](https://mlsanity.com/paper/2101.01133/) (2021)
- [Lite-Mono: A Lightweight CNN and Transformer Architecture for Self-Supervised Monocular Depth Estimation](https://mlsanity.com/paper/2211.13202/) (2022)
- [Endo-Depth-and-Motion: Reconstruction and Tracking in Endoscopic Videos using Depth Networks and Photometric Constraints](https://mlsanity.com/paper/2103.16525/) (2021)
- [Self-Supervised Monocular Depth and Ego-Motion Estimation in Endoscopy: Appearance Flow to the Rescue](https://mlsanity.com/paper/2112.08122/) (2021)
- [Unsupervised Learning for Intrinsic Image Decomposition from a Single Image](https://mlsanity.com/paper/1911.09930/) (2019)
- [EndoDAC: Efficient Adapting Foundation Model for Self-Supervised Depth Estimation from Any Endoscopic Camera](https://mlsanity.com/paper/2405.08672/) (2024)
- [SERV-CT: A disparity dataset from CT for validation of endoscopic 3D reconstruction](https://mlsanity.com/paper/2012.11779/) (2020)
- [MonoPCC: Photometric-invariant Cycle Constraint for Monocular Depth Estimation of Endoscopic Images](https://mlsanity.com/paper/2404.16571/) (2024)

## Abstract (arXiv)

Depth estimation is a significant task for 3D perception in endoscopic surgeries. However, illumination interference and feature diversity in various endoscopic scenes are still challenges for generalizable depth estimation and ego-motion estimation. Based on this, a novel self-supervised framework, EndoMINI, is proposed for depth estimation in endoscopic scenes. Specifically, mixture of low-rank experts (MiLoRE) is proposed to perform parameter-efficient fine-tuning, which can also boost the model adaptation to scenes with different characteristics. Meanwhile, an intrinsic image alignment (IIA) is introduced into the training loss to alleviate the influence of light reflectance in endoscopy with a novel intrinsic image decomposition network. The proposed method is evaluated on SCARED datasets for supervised depth estimation, and two endoscopic datasets, Hamlyn and SERV-CT, for zero-shot depth estimation, compared with state-of-the-art works as well. The experimental results demonstrate outstanding performance of the proposed model and the effects of the main contributions.