# LabEvolver: Training-Free Experience Evolution for Safe and Grounded Wet-Lab Agents

arXiv: https://arxiv.org/abs/2607.27690 · HTML: https://mlsanity.com/paper/2607.27690/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 24 of its 42 references that are in the map.
- First posted on arXiv 30 Jul 2026.

## Builds on (most cited first, 24 of 24)

- [ReAct: Synergizing Reasoning and Acting in Language Models](https://mlsanity.com/paper/2210.03629/) (2022)
- [Reflexion: Language Agents with Verbal Reinforcement Learning](https://mlsanity.com/paper/2303.11366/) (2023)
- [Self-Refine: Iterative Refinement with Self-Feedback](https://mlsanity.com/paper/2303.17651/) (2023)
- [RT-2: Vision-Language-Action Models Transfer Web Knowledge to Robotic Control](https://mlsanity.com/paper/2307.15818/) (2023)
- [Do As I Can, Not As I Say: Grounding Language in Robotic Affordances](https://mlsanity.com/paper/2204.01691/) (2022)
- [Voyager: An Open-Ended Embodied Agent with Large Language Models](https://mlsanity.com/paper/2305.16291/) (2023)
- [PaLM-E: An Embodied Multimodal Language Model](https://mlsanity.com/paper/2303.03378/) (2023)
- [RT-1: Robotics Transformer for Real-World Control at Scale](https://mlsanity.com/paper/2212.06817/) (2022)
- [Code as Policies: Language Model Programs for Embodied Control](https://mlsanity.com/paper/2209.07753/) (2022)
- [ALFWorld: Aligning Text and Embodied Environments for Interactive Learning](https://mlsanity.com/paper/2010.03768/) (2020)
- [DeepSeek-V4: Towards Highly Efficient Million-Token Context Intelligence](https://mlsanity.com/paper/2606.19348/) (2026)
- [ExpeL: LLM Agents Are Experiential Learners](https://mlsanity.com/paper/2308.10144/) (2023)
- [Open X-Embodiment: Robotic Learning Datasets and RT-X Models](https://mlsanity.com/paper/2310.08864/) (2023)
- [DROID: A Large-Scale In-The-Wild Robot Manipulation Dataset](https://mlsanity.com/paper/2403.12945/) (2024)
- [ChemCrow: Augmenting large-language models with chemistry tools](https://mlsanity.com/paper/2304.05376/) (2023)
- [ProgPrompt: Generating Situated Robot Task Plans using Large Language Models](https://mlsanity.com/paper/2209.11302/) (2022)
- [SkillRL: Evolving Agents via Recursive Skill-Augmented Reinforcement Learning](https://mlsanity.com/paper/2602.08234/) (2026)
- [Trace2Skill: Distill Trajectory-Local Lessons into Transferable Agent Skills](https://mlsanity.com/paper/2603.25158/) (2026)
- [RoboAgent: Generalization and Efficiency in Robot Manipulation via Semantic Augmentations and Action Chunking](https://mlsanity.com/paper/2309.01918/) (2023)
- [G-Memory: Tracing Hierarchical Memory for Multi-Agent Systems](https://mlsanity.com/paper/2506.07398/) (2025)
- [Memp: Exploring Agent Procedural Memory](https://mlsanity.com/paper/2508.06433/) (2025)
- [ORGANA: A Robotic Assistant for Automated Chemistry Experimentation and Characterization](https://mlsanity.com/paper/2401.06949/) (2024)
- [Empowering Large Language Model Agents through Action Learning](https://mlsanity.com/paper/2402.15809/) (2024)
- [ELITE: Experiential Learning and Intent-Aware Transfer for Self-improving Embodied Agents](https://mlsanity.com/paper/2603.24018/) (2026)

## Abstract (arXiv)

We introduce LabEvolver, a training-free framework that equips safe and grounded wet-lab agents with episodic memory from execution experience. LabEvolver couples a state-grounded inner trial loop for adaptive perception, online planning, and safety validation with an outer evolution loop that distills completed trajectories into reusable skill, strategy, and safety experience. On robotic solution-preparation tasks, LabEvolver demonstrates real-world feasibility, reducing pH-regulation completion time and safety-gate intercepts by 48.2% and 60.0%, respectively. On ALFWorld, it further improves cumulative success rate within 20 steps from 76.2% with ReAct to 91.4% over 500 continual tasks, showing generality beyond wet-lab settings. These results support learn-by-doing experience evolution as a feasible path toward closed-loop automated scientific discovery. The project page is available at https://andygao6186.github.io/LabEvolver/.