# CrossSpine: Multi-scale Cross-sequence Attention with Anatomical Priors for Automated Pfirrmann Grading

arXiv: https://arxiv.org/abs/2607.22728 · HTML: https://mlsanity.com/paper/2607.22728/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 7 of its 17 references that are in the map.
- First posted on arXiv 22 Jul 2026.

## Builds on (most cited first, 7 of 7)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [ImageNet Large Scale Visual Recognition Challenge](https://mlsanity.com/paper/1409.0575/) (2014)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [Predicting Depth, Surface Normals and Semantic Labels with a Common Multi-Scale Convolutional Architecture](https://mlsanity.com/paper/1411.4734/) (2014)
- [A Stronger Baseline For Automatic Pfirrmann Grading Of Lumbar Spine MRI Using Deep Learning](https://mlsanity.com/paper/2210.14597/) (2022)

## Built on by (most cited first, 1 of 1)

- [GateSPINE: Gated Cross-View Fusion for Lumbar Spine MRI Report Generation](https://mlsanity.com/paper/2609.40091/) (2026)

## Abstract (arXiv)

Automated grading of Lumbar Disc Degeneration is essential for the objective quantification of structural changes associated with low back pain. Observing that baseline models underperformed on our data, we propose a framework designed to overcome these limitations. First, we present the Cross-sequence Attention Spine (CrossSpine) framework, a novel architecture that employs a cross-sequence attention mechanism to adaptively fuse features from different MRI sequences at multiple spa- tial scales. Second, we contribute a meticulously curated dataset aimed at automated Pfirrmann grading. Finally, we introduce an IVD-aware classification technique that integrates anatomical disc-level information, enabling the model to learn level-specific degeneration priors. Our experi- ments demonstrate the superiority of this approach: CrossSpine achieved a relative improvement exceeding 125% in the Macro F1 score, while boosting the Mean AUPRC by 99% and the Mean AUROC by 36% com- pared to the baseline.
