# Understanding From Human Perspective: A Multi-agent System for Interactive Egocentric Medical Image Segmentation

arXiv: https://arxiv.org/abs/2607.17341 · HTML: https://mlsanity.com/paper/2607.17341/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 35 of its 58 references that are in the map.
- First posted on arXiv 19 Jul 2026.

## Builds on (most cited first, 30 of 35)

- [Grounding DINO: Marrying DINO with Grounded Pre-Training for Open-Set Object Detection](https://mlsanity.com/paper/2303.05499/) (2023)
- [SAM 2: Segment Anything in Images and Videos](https://mlsanity.com/paper/2408.00714/) (2024)
- [Ego4D: Around the World in 3,000 Hours of Egocentric Video](https://mlsanity.com/paper/2110.07058/) (2021)
- [Grounded SAM: Assembling Open-World Models for Diverse Visual Tasks](https://mlsanity.com/paper/2401.14159/) (2024)
- [SAM 3: Segment Anything with Concepts](https://mlsanity.com/paper/2511.16719/) (2025)
- [Scaling Egocentric Vision: The EPIC-KITCHENS Dataset](https://mlsanity.com/paper/1804.02748/) (2018)
- [LISA: Reasoning Segmentation via Large Language Model](https://mlsanity.com/paper/2308.00692/) (2023)
- [AMOS: A Large-Scale Abdominal Multi-Organ Benchmark for Versatile Medical Image Segmentation](https://mlsanity.com/paper/2206.08023/) (2022)
- [Deep Learning for Segmentation using an Open Large-Scale Dataset in 2D Echocardiography](https://mlsanity.com/paper/1908.06948/) (2019)
- [AgentClinic: a multimodal agent benchmark to evaluate AI in simulated clinical environments](https://mlsanity.com/paper/2405.07960/) (2024)
- [Grounding DINO 1.5: Advance the "Edge" of Open-Set Object Detection](https://mlsanity.com/paper/2405.10300/) (2024)
- [DeepIGeoS: A Deep Interactive Geodesic Framework for Medical Image Segmentation](https://mlsanity.com/paper/1707.00652/) (2017)
- [An Outlook into the Future of Egocentric Vision](https://mlsanity.com/paper/2308.07123/) (2023)
- [A multi-centre polyp detection and segmentation dataset for generalisability assessment](https://mlsanity.com/paper/2106.04463/) (2021)
- [CLAMBER: A Benchmark of Identifying and Clarifying Ambiguous Information Needs in Large Language Models](https://mlsanity.com/paper/2405.12063/) (2024)
- [EgoTextVQA: Towards Egocentric Scene-Text Aware Video Question Answering](https://mlsanity.com/paper/2502.07411/) (2025)
- [Omnia de EgoTempo: Benchmarking Temporal Understanding of Multi-Modal LLMs in Egocentric Videos](https://mlsanity.com/paper/2503.13646/) (2025)
- [Self-Evolving Multi-Agent Simulations for Realistic Clinical Interactions](https://mlsanity.com/paper/2503.22678/) (2025)
- [Agent-Oriented Planning in Multi-Agent Systems](https://mlsanity.com/paper/2410.02189/) (2024)
- [EventEgo3D: 3D Human Motion Capture from Egocentric Event Streams](https://mlsanity.com/paper/2404.08640/) (2024)
- [MedSAM3: Delving into Segment Anything with Medical Concepts](https://mlsanity.com/paper/2511.19046/) (2025)
- [EgoSurgery-Phase: A Dataset of Surgical Phase Recognition from Egocentric Open Surgery Videos](https://mlsanity.com/paper/2405.19644/) (2024)
- [ReflecTool: Towards Reflection-Aware Tool-Augmented Clinical Agents](https://mlsanity.com/paper/2410.17657/) (2024)
- [Challenges and Trends in Egocentric Vision: A Survey](https://mlsanity.com/paper/2503.15275/) (2025)
- [PRISM: A Promptable and Robust Interactive Segmentation Model with Visual Prompts](https://mlsanity.com/paper/2404.15028/) (2024)
- [Temporally-Extended Prompts Optimization for SAM in Interactive Medical Image Segmentation](https://mlsanity.com/paper/2306.08958/) (2023)
- [A Multimodal Multi-Agent Framework for Radiology Report Generation](https://mlsanity.com/paper/2505.09787/) (2025)
- [SimTxtSeg: Weakly-Supervised Medical Image Segmentation with Simple Text Cues](https://mlsanity.com/paper/2406.19364/) (2024)
- [Cognition Transferring and Decoupling for Text-supervised Egocentric Semantic Segmentation](https://mlsanity.com/paper/2410.01341/) (2024)
- [Medical AI Consensus: A Multi-Agent Framework for Radiology Report Generation and Evaluation](https://mlsanity.com/paper/2509.17353/) (2025)

## Abstract (arXiv)

Interactive egocentric medical image segmentation (IEMIS) plays an important role in smart-glasses-assisted medical image review, segmenting the medical targets a clinician refers to from their egocentric view. Once it succeeds, the object-level visual evidence it provides strengthens the review and underpins fine-grained analysis and clinical decision-making. However, the instruction and the video both come from the user's egocentric perspective, which poses two challenges. (1) Semantic ambiguity leaves the model unable to confirm the user-intended target. (2) Visual variability makes the segmentation jump from frame to frame. In this paper, we propose EgoMed-Agent, a multi-agent system that understands the target from the human perspective through two workflows. (1) The textitTarget Confirmation Workflow grounds the instruction against candidate targets with a reliability score, confirming the target when the grounding is reliable and asking the user to clarify when it is not, thereby confirming the segmentation target. (2) The textitLocalization-Guided Propagation Workflow couples mask propagation with per-frame target localization, using the localized target to correct the propagated mask whenever the two diverge, so the segmentation stays on the target across the egocentric video. Extensive experiments show that EgoMed-Agent reaches 71.34% average Dice, far above the best text-prompted baseline (11.70%). Our code is available at hrefhttps://github.com/wdyyyyyy/EgoMed-Agentour project page.