# MIS-HCC: Hierarchical Channel Clustering for Efficient Medical Image Segmentation

arXiv: https://arxiv.org/abs/2607.17329 · HTML: https://mlsanity.com/paper/2607.17329/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- Builds on 47 of its 66 references that are in the map.
- First posted on arXiv 19 Jul 2026.

## Builds on (most cited first, 30 of 47)

- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Similarity of Neural Network Representations Revisited](https://mlsanity.com/paper/1905.00414/) (2019)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [UNet++: A Nested U-Net Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1807.10165/) (2018)
- [Pruning Filters for Efficient ConvNets](https://mlsanity.com/paper/1608.08710/) (2016)
- [Learning Efficient Convolutional Networks through Network Slimming](https://mlsanity.com/paper/1708.06519/) (2017)
- [Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1902.03368/) (2019)
- [Filter Pruning via Geometric Median for Deep Convolutional Neural Networks Acceleration](https://mlsanity.com/paper/1811.00250/) (2018)
- [HRank: Filter Pruning using High-Rank Feature Map](https://mlsanity.com/paper/2002.10179/) (2020)
- [FakeShield: Explainable Image Forgery Detection and Localization via Multi-modal Large Language Models](https://mlsanity.com/paper/2410.02761/) (2024)
- [MedSAM2: Segment Anything in 3D Medical Images and Videos](https://mlsanity.com/paper/2504.03600/) (2025)
- [Frequency-Aligned Knowledge Distillation for Lightweight Spatiotemporal Forecasting](https://mlsanity.com/paper/2507.02939/) (2025)
- [CHEX: CHannel EXploration for CNN Model Compression](https://mlsanity.com/paper/2203.15794/) (2022)
- [SepPrune: Structured Pruning for Efficient Deep Speech Separation](https://mlsanity.com/paper/2505.12079/) (2025)
- [DRP: Distilled Reasoning Pruning with Skill-aware Step Decomposition for Efficient Large Reasoning Models](https://mlsanity.com/paper/2505.13975/) (2025)
- [Unsupervised Hyperspectral Image Super-Resolution via Self-Supervised Modality Decoupling](https://mlsanity.com/paper/2412.04802/) (2024)
- [ACAM-KD: Adaptive and Cooperative Attention Masking for Knowledge Distillation](https://mlsanity.com/paper/2503.06307/) (2025)
- [Trainability Preserving Neural Pruning](https://mlsanity.com/paper/2207.12534/) (2022)
- [Vision-Language Embodiment for Monocular Depth Estimation](https://mlsanity.com/paper/2503.16535/) (2025)
- [Reasoning-Enhanced Domain-Adaptive Pretraining of Multimodal Large Language Models for Short Video Content Governance](https://mlsanity.com/paper/2509.21486/) (2025)
- [Audio-Enhanced Vision-Language Modeling with Latent Space Broadening for High Quality Data Expansion](https://mlsanity.com/paper/2503.17551/) (2025)
- [MaPPO: Maximum a Posteriori Preference Optimization with Prior Knowledge](https://mlsanity.com/paper/2507.21183/) (2025)
- [Learning How to Use Tools, Not Just When: Pattern-Aware Tool-Integrated Reasoning](https://mlsanity.com/paper/2509.23292/) (2025)
- [Find Your Optimal Teacher: Personalized Data Synthesis via Router-Guided Multi-Teacher Distillation](https://mlsanity.com/paper/2510.10925/) (2025)
- [Neural Clustering based Visual Representation Learning](https://mlsanity.com/paper/2403.17409/) (2024)
- [MPQ-DMv2: Flexible Residual Mixed Precision Quantization for Low-Bit Diffusion Models with Temporal Distillation](https://mlsanity.com/paper/2507.04290/) (2025)
- [Render-in-the-Loop: Vector Graphics Generation via Visual Self-Feedback](https://mlsanity.com/paper/2604.20730/) (2026)
- [ANTS: Adaptive Negative Textual Space Shaping for OOD Detection via Test-Time MLLM Understanding and Reasoning](https://mlsanity.com/paper/2509.03951/) (2025)
- [Embodiment: Self-Supervised Depth Estimation Based on Camera Models](https://mlsanity.com/paper/2408.01565/) (2024)

## Built on by (most cited first, 4 of 4)

- [Decision-Oriented Uncertainty Quantification for Risk Control in Earth System Spatiotemporal Foundation Models](https://mlsanity.com/paper/2609.14821/) (2026)
- [MedTRACE: Tool-Augmented Multimodal Clinical Reasoning Agents for Evidence-Grounded Decision-Making](https://mlsanity.com/paper/2609.14823/) (2026)
- [AsyncCouple-Flow: Asynchronous Cross-Modal Coupling and Flow Matching for Spatio-Temporal Forecasting](https://mlsanity.com/paper/2609.16573/) (2026)
- [CoRe: Coherence and Relational Alignment for Multivariate Time Series Forecasting](https://mlsanity.com/paper/2609.19670/) (2026)

## Abstract (arXiv)

Medical image segmentation models require both high accuracy and lightweight design to accommodate real-world medical applications. The deployment of these models on resource-limited medical platforms remains a significant challenge due to their high computational and parameter requirements. Existing pruning methods for model compression mostly overlook the intrinsic connections and similarity between the internal structures of complex deep neural networks. As a result, compressed models may not effectively retain the basic features of the pretrained network. To solve this problem, we propose a hierarchical clustering compression method for medical image segmentation models (MIS-HCC). This approach employs hierarchical clustering to partition channels and fuse their parameters efficiently. Specifically, it leverages the Wasserstein distance to represent similarity of channels within layers of pre-trained network, forming a similarity matrix that guides the clustering process. Channels within each cluster are then fused to produce a compressed network. Experimental results on three medical image datasets application demonstrate that MIS-HCC outperforms the state-of-the-art methods in both accuracy and compression efficiency, offering an effective solution for deploying medical image segmentation models on resource-limited medical platforms.