# From Optimal Policies to Individual Differences: Rethinking Reinforcement Learning for Biology

arXiv: https://arxiv.org/abs/2607.16542 · HTML: https://mlsanity.com/paper/2607.16542/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in RL for games and combinatorial optimization, one of 15 directions in Deep reinforcement learning methods.
- Builds on 22 of its 56 references that are in the map.
- First posted on arXiv 17 Jul 2026.

## Placed in

- Deep reinforcement learning methods / [RL for games and combinatorial optimization](https://mlsanity.com/deeprl/rl-for-games-and-combinatorial-optimization/)

## Builds on (most cited first, 22 of 22)

- [A Distributional Perspective on Reinforcement Learning](https://mlsanity.com/paper/1707.06887/) (2017)
- [Diversity is All You Need: Learning Skills without a Reward Function](https://mlsanity.com/paper/1802.06070/) (2018)
- [Is Independent Learning All You Need in the StarCraft Multi-Agent Challenge?](https://mlsanity.com/paper/2011.09533/) (2020)
- [Learning to Adapt in Dynamic, Real-World Environments Through Meta-Reinforcement Learning](https://mlsanity.com/paper/1803.11347/) (2018)
- [The Primacy Bias in Deep Reinforcement Learning](https://mlsanity.com/paper/2205.07802/) (2022)
- [A Generalized Algorithm for Multi-Objective Reinforcement Learning and Policy Adaptation](https://mlsanity.com/paper/1908.08342/) (2019)
- [Exploration in Deep Reinforcement Learning: A Survey](https://mlsanity.com/paper/2205.00824/) (2022)
- [Dynamic Weights in Multi-Objective Deep Reinforcement Learning](https://mlsanity.com/paper/1809.07803/) (2018)
- [Celebrating Diversity in Shared Multi-Agent Reinforcement Learning](https://mlsanity.com/paper/2106.02195/) (2021)
- [Intrinsically Motivated Goal Exploration Processes with Automatic Curriculum Learning](https://mlsanity.com/paper/1708.02190/) (2017)
- [Deep Online Learning via Meta-Learning: Continual Adaptation for Model-Based RL](https://mlsanity.com/paper/1812.07671/) (2018)
- [A multi-agent reinforcement learning model of common-pool resource appropriation](https://mlsanity.com/paper/1707.06600/) (2017)
- [The Option Keyboard: Combining Skills in Reinforcement Learning](https://mlsanity.com/paper/2106.13105/) (2021)
- [Distributional Reinforcement Learning for Efficient Exploration](https://mlsanity.com/paper/1905.06125/) (2019)
- [Learning Transferable Cooperative Behavior in Multi-Agent Teams](https://mlsanity.com/paper/1906.01202/) (2019)
- [AdaSociety: An Adaptive Environment with Social Structures for Multi-Agent Decision-Making](https://mlsanity.com/paper/2411.03865/) (2024)
- [Towards a Theory of Evolution as Multilevel Learning](https://mlsanity.com/paper/2110.14602/) (2021)
- [Let's Play Again: Variability of Deep Reinforcement Learning Agents in Atari Environments](https://mlsanity.com/paper/1904.06312/) (2019)
- [The Nature of Temporal Difference Errors in Multi-step Distributional Reinforcement Learning](https://mlsanity.com/paper/2207.07570/) (2022)
- [Emergent collective intelligence from massive-agent cooperation and competition](https://mlsanity.com/paper/2301.01609/) (2023)
- [Habits and goals in synergy: a variational Bayesian framework for behavior](https://mlsanity.com/paper/2304.05008/) (2023)
- [Depression as a disorder of distributional coding](https://mlsanity.com/paper/2507.16598/) (2025)

## Abstract (arXiv)

Reinforcement learning (RL) is primarily known as a computational method for optimizing control tasks, but it is increasingly used to explain biological behavior. While RL successfully captures key aspects of biology, a major gap remains: between-agent behavioral variability. Consistent individual differences naturally permeate biological populations, yet RL models typically present only the single best individual or the population average. Addressing this gap requires moving beyond current practices to generate behavioral diversity using biologically plausible mechanisms. Here, we examine approaches from various subfields of RL and outline potential paths forward to close the gap between biology and simulation.
