# Cura 1T: Specialized Model for Agentic Healthcare

arXiv: https://arxiv.org/abs/2607.15314 · HTML: https://mlsanity.com/paper/2607.15314/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use.
- Builds on 30 of its 35 references that are in the map.
- First posted on arXiv 15 Jul 2026.

## Placed in

- LLM agents and tool use / [Medical and scientific domain agents](https://mlsanity.com/agents/medical-and-scientific-domain-agents/)

## Builds on (most cited first, 30 of 30)

- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [Reflexion: Language Agents with Verbal Reinforcement Learning](https://mlsanity.com/paper/2303.11366/) (2023)
- [Self-Refine: Iterative Refinement with Self-Feedback](https://mlsanity.com/paper/2303.17651/) (2023)
- [GPQA: A Graduate-Level Google-Proof Q&A Benchmark](https://mlsanity.com/paper/2311.12022/) (2023)
- [Large Language Models Encode Clinical Knowledge](https://mlsanity.com/paper/2212.13138/) (2022)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [The AI Scientist: Towards Fully Automated Open-Ended Scientific Discovery](https://mlsanity.com/paper/2408.06292/) (2024)
- [STaR: Bootstrapping Reasoning With Reasoning](https://mlsanity.com/paper/2203.14465/) (2022)
- [AlphaEvolve: A coding agent for scientific and algorithmic discovery](https://mlsanity.com/paper/2506.13131/) (2025)
- [Large Language Models as Optimizers](https://mlsanity.com/paper/2309.03409/) (2023)
- [DSPy: Compiling Declarative Language Model Calls into Self-Improving Pipelines](https://mlsanity.com/paper/2310.03714/) (2023)
- [τ2-Bench: Evaluating Conversational Agents in a Dual-Control Environment](https://mlsanity.com/paper/2506.07982/) (2025)
- [MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answering](https://mlsanity.com/paper/2203.14371/) (2022)
- [HealthBench: Evaluating Large Language Models Towards Improved Human Health](https://mlsanity.com/paper/2505.08775/) (2025)
- [Scaling Relationship on Learning Mathematical Reasoning with Large Language Models](https://mlsanity.com/paper/2308.01825/) (2023)
- [The AI Scientist-v2: Workshop-Level Automated Scientific Discovery via Agentic Tree Search](https://mlsanity.com/paper/2504.08066/) (2025)
- [TextGrad: Automatic "Differentiation" via Text](https://mlsanity.com/paper/2406.07496/) (2024)
- [Self-Distillation Enables Continual Learning](https://mlsanity.com/paper/2601.19897/) (2026)
- [AgentClinic: a multimodal agent benchmark to evaluate AI in simulated clinical environments](https://mlsanity.com/paper/2405.07960/) (2024)
- [MedXpertQA: Benchmarking Expert-Level Medical Reasoning and Understanding](https://mlsanity.com/paper/2501.18362/) (2025)
- [MedAgentBench: A Realistic Virtual EHR Environment to Benchmark Medical LLM Agents](https://mlsanity.com/paper/2501.14654/) (2025)
- [HealthBench Professional: Evaluating Large Language Models on Real Clinician Chats](https://mlsanity.com/paper/2604.27470/) (2026)
- [ResearchGym: Evaluating Language Model Agents on Real-World AI Research](https://mlsanity.com/paper/2602.15112/) (2026)
- [PhysicianBench: Evaluating LLM Agents in Real-World EHR Environments](https://mlsanity.com/paper/2605.02240/) (2026)
- [AutoResearch AI: Towards AI-Powered Research Automation for Scientific Discovery](https://mlsanity.com/paper/2605.23204/) (2026)
- [CHI-Bench: Can AI Agents Automate End-to-End, Long-Horizon, Policy-Rich Healthcare Workflows?](https://mlsanity.com/paper/2605.16679/) (2026)
- [HealthAgentBench: A Unified Benchmark Suite of Realistic Agentic Healthcare Environments for Challenging Frontier AI Agents](https://mlsanity.com/paper/2606.31179/) (2026)
- [ClinAlign: Scaling Healthcare Alignment from Clinician Preference](https://mlsanity.com/paper/2602.09653/) (2026)
- [Baichuan-M4: A Clinical-Grade Medical Agent System for Continuous Care](https://mlsanity.com/paper/2606.08982/) (2026)

## Abstract (arXiv)

Healthcare spans high-stakes communication, expert reasoning, and workflow execution, yet specialized language models that cover these use cases together remain limited. A healthcare model must handle patient consultation, clinical reasoning over text and images, interactive diagnosis, and electronic health record (EHR) tool use. These capabilities fail in different ways, and a narrow update for one task can degrade another. We present Cura 1T, a healthcare foundation model trained through recursive self-improvement (RSI). In each RSI round, the RSI harness runs the current model on healthcare benchmarks, evaluates the trajectories to locate capability gaps, and refines the training mixture by synthesizing training data. On 6 healthcare benchmarks, Cura 1T scores highest on MedAgentBench, HealthBench Professional, HealthBench Hard, MedXpertQA text, and AgentClinic, and second on MedXpertQA multimodal. It preserves performances on out-of-domain reasoning and agentic benchmarks including AIME, GPQA-Diamond, and τ2-Bench.