# Generalized Neural Distributional Regression

arXiv: https://arxiv.org/abs/2607.14122 · HTML: https://mlsanity.com/paper/2607.14122/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 3 of its 44 references that are in the map.
- First posted on arXiv 16 Jun 2026.

## Builds on (most cited first, 3 of 3)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [Decoupled Weight Decay Regularization](https://mlsanity.com/paper/1711.05101/) (2017)
- [Neural Mixture Distributional Regression](https://mlsanity.com/paper/2010.06889/) (2020)

## Abstract (arXiv)

We introduce the Generalized Neural Distributional Regression (GNDR) framework, which seamlessly embeds deep neural networks into the parameter space of classical probability distributions. To reconcile the inherent non-identifiability of deep architectures with maximum likelihood theory, we propose a two-step semi-parametric estimation procedure. By isolating the terminal prediction heads and treating the upstream network as a fixed, non-linear basis expansion, GNDR enables the extraction of analytical Fisher Information matrices. This facilitates rigorous uncertainty quantification, generating observation-specific confidence bands and tolerance intervals via the multivariate Delta method. We demonstrate the framework's versatility and superior distributional calibration across diverse data modalities, including overdispersed clinical counts, right-censored transcriptomic survival profiles under a mixture cure framework, and zero-truncated age distributions derived directly from unstructured facial images. The methodology is natively implemented in the open-source Python package textitthetaflow.
