# A Large Language Model-Driven Agent-Based Modeling Framework with Multi-Round Communication for Simulating Vaccine Opinion Dynamics

arXiv: https://arxiv.org/abs/2607.07387 · HTML: https://mlsanity.com/paper/2607.07387/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Social simulation and multi-agent debate, one of 16 directions in LLM agents and tool use.
- Builds on 8 of its 21 references that are in the map.
- First posted on arXiv 8 Jul 2026.

## Placed in

- LLM agents and tool use / [Social simulation and multi-agent debate](https://mlsanity.com/agents/social-simulation-and-multi-agent-debate/)

## Builds on (most cited first, 8 of 8)

- [ReAct: Synergizing Reasoning and Acting in Language Models](https://mlsanity.com/paper/2210.03629/) (2022)
- [A Survey on the Memory Mechanism of Large Language Model based Agents](https://mlsanity.com/paper/2404.13501/) (2024)
- [Simulating Opinion Dynamics with Networks of LLM-based Agents](https://mlsanity.com/paper/2311.09618/) (2023)
- [Igniting Language Intelligence: The Hitchhiker's Guide From Chain-of-Thought Reasoning to Language Agents](https://mlsanity.com/paper/2311.11797/) (2023)
- [Do Large Language Models Solve the Problems of Agent-Based Modeling? A Critical Review of Generative Social Simulations](https://mlsanity.com/paper/2504.03274/) (2025)
- [The PIMMUR Principles: Ensuring Validity in Collective Behavior of LLM Societies](https://mlsanity.com/paper/2509.18052/) (2025)
- [Simulating Society Requires Simulating Thought](https://mlsanity.com/paper/2506.06958/) (2025)
- [Simulating Generative Social Agents via Theory-Informed Workflow Design](https://mlsanity.com/paper/2508.08726/) (2025)

## Abstract (arXiv)

Recently, Large Language Models (LLMs) have been utilized in various applications of computational social science and provide the possibility to integrate such models into agent-based modeling to explore the cognitive processes. However, how specific cognitive modules drive individual decisions and macro-level opinion dynamics remains unclear. Therefore, this study introduces a framework that integrates an LLM (Qwen3-8B) into agent-based modeling to investigate this problem, using vaccination opinion dynamics as a case study. We utilize this framework to simulate opinion dynamics among agents with heterogeneous profiles and social networks, evaluating scenarios by enabling different cognitive modules: a memory module and a prompt diversity module. The simulation results reveal that different cognitive modules have opposite impacts on our emergent opinion. Furthermore, the framework reproduces the non-linear behavior patterns of social influence observed in existing research, demonstrating our framework's validity and potential to reach the level 3 validation of agent-based models.