# ReMoDEx: A Local-to-Global Relevance-Based Model Decision Explainability Framework for large-Scale Image Datasets

arXiv: https://arxiv.org/abs/2607.06889 · HTML: https://mlsanity.com/paper/2607.06889/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 25 of its 44 references that are in the map.
- First posted on arXiv 8 Jul 2026.

## Builds on (most cited first, 25 of 25)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [A Unified Approach to Interpreting Model Predictions](https://mlsanity.com/paper/1705.07874/) (2017)
- ["Why Should I Trust You?": Explaining the Predictions of Any Classifier](https://mlsanity.com/paper/1602.04938/) (2016)
- [Axiomatic Attribution for Deep Networks](https://mlsanity.com/paper/1703.01365/) (2017)
- [Visualizing and Understanding Convolutional Networks](https://mlsanity.com/paper/1311.2901/) (2013)
- [Shortcut Learning in Deep Neural Networks](https://mlsanity.com/paper/2004.07780/) (2020)
- [Explainable Artificial Intelligence (XAI): Concepts, Taxonomies, Opportunities and Challenges toward Responsible AI](https://mlsanity.com/paper/1910.10045/) (2019)
- [A Survey on Deep Learning in Medical Image Analysis](https://mlsanity.com/paper/1702.05747/) (2017)
- [Grad-CAM++: Improved Visual Explanations for Deep Convolutional Networks](https://mlsanity.com/paper/1710.11063/) (2017)
- [A Survey on Explainable Artificial Intelligence (XAI): Towards Medical XAI](https://mlsanity.com/paper/1907.07374/) (2019)
- [Confounding variables can degrade generalization performance of radiological deep learning models](https://mlsanity.com/paper/1807.00431/) (2018)
- [Unmasking Clever Hans Predictors and Assessing What Machines Really Learn](https://mlsanity.com/paper/1902.10178/) (2019)
- [Methods for Interpreting and Understanding Deep Neural Networks](https://mlsanity.com/paper/1706.07979/) (2017)
- [Hidden Stratification Causes Clinically Meaningful Failures in Machine Learning for Medical Imaging](https://mlsanity.com/paper/1909.12475/) (2019)
- [Deep Convolutional Neural Networks for Computer-Aided Detection: CNN Architectures, Dataset Characteristics and Transfer Learning](https://mlsanity.com/paper/1602.03409/) (2016)
- [Can AI help in screening Viral and COVID-19 pneumonia?](https://mlsanity.com/paper/2003.13145/) (2020)
- [Common pitfalls and recommendations for using machine learning to detect and prognosticate for COVID-19 using chest radiographs and CT scans](https://mlsanity.com/paper/2008.06388/) (2020)
- [Detecting Shortcut Learning for Fair Medical AI using Shortcut Testing](https://mlsanity.com/paper/2207.10384/) (2022)
- [Improving deep neural network generalization and robustness to background bias via layer-wise relevance propagation optimization](https://mlsanity.com/paper/2202.00232/) (2022)
- [Detecting Shortcuts in Medical Images -- A Case Study in Chest X-rays](https://mlsanity.com/paper/2211.04279/) (2022)
- [Shortcut Learning in Medical Image Segmentation](https://mlsanity.com/paper/2403.06748/) (2024)
- [Impact of lung segmentation on the diagnosis and explanation of COVID-19 in chest X-ray images](https://mlsanity.com/paper/2009.09780/) (2020)
- [COVID-19 detection using chest X-rays: is lung segmentation important for generalization?](https://mlsanity.com/paper/2104.06176/) (2021)

## Abstract (arXiv)

Deep learning image classifiers achieve strong predictive performance yet remain opaque in how decisions are formed. A model may predict correctly while relying on irrelevant cues, shortcut associations, peripheral structures, or device level artifacts instead of task relevant regions. On large scale datasets this opacity is especially problematic, since inspecting heatmaps one sample at a time cannot scale to thousands of predictions. We propose Relevance Based Model Decision Explainability (ReMoDEx), a framework for systematic, dataset scale assessment of model decision behaviour in image classification. ReMoDEx defines a stepwise pipeline: model inference, target class selection, relevance map generation, heatmap standardisation, similarity based grouping of patterns, cluster level interpretation, and spatial relevance assessment. Local methods GradCAM++, Integrated Gradients, Occlusion Sensitivity, and Layerwise Relevance Propagation are each combined independently with a single global module that summarises an entire set of relevance maps into a few decision strategy clusters, replacing sample by sample inspection with an automatic, scalable summary. To demonstrate ReMoDEx, we applied it to a VGG16 based classifier distinguishing COVID-19, Normal, Lung Opacity, and Viral Pneumonia. The classifier showed stable performance (86.27% test accuracy, 0.9624 test AUC). However, each explainer combined with the global module consistently produced two recurring strategies: central thoracic region decisions and border/corner sensitive decisions, indicating possible shortcut learning that conventional metrics could not reveal. Masked image validation confirmed that model confidence and predicted class changed when central or peripheral regions were occluded. ReMoDEx thus provides a scalable relevance based decision assessment framework and an essential complement to accuracy based evaluation.