# Readable but Not Controllable: Neuron-Level Evidence for Medical LLM Hallucination

arXiv: https://arxiv.org/abs/2607.00158 · HTML: https://mlsanity.com/paper/2607.00158/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 18 of its 21 references that are in the map.
- First posted on arXiv 30 Jun 2026.

## Builds on (most cited first, 18 of 18)

- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [Inference-Time Intervention: Eliciting Truthful Answers from a Language Model](https://mlsanity.com/paper/2306.03341/) (2023)
- [PubMedQA: A Dataset for Biomedical Research Question Answering](https://mlsanity.com/paper/1909.06146/) (2019)
- [Steering Llama 2 via Contrastive Activation Addition](https://mlsanity.com/paper/2312.06681/) (2023)
- [SelfCheckGPT: Zero-Resource Black-Box Hallucination Detection for Generative Large Language Models](https://mlsanity.com/paper/2303.08896/) (2023)
- [Discovering Latent Knowledge in Language Models Without Supervision](https://mlsanity.com/paper/2212.03827/) (2022)
- [The Internal State of an LLM Knows When It's Lying](https://mlsanity.com/paper/2304.13734/) (2023)
- [MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answering](https://mlsanity.com/paper/2203.14371/) (2022)
- [Hallucination is Inevitable: An Innate Limitation of Large Language Models](https://mlsanity.com/paper/2401.11817/) (2024)
- [BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domains](https://mlsanity.com/paper/2402.10373/) (2024)
- [HaloScope: Harnessing Unlabeled LLM Generations for Hallucination Detection](https://mlsanity.com/paper/2409.17504/) (2024)
- [Reducing hallucination in structured outputs via Retrieval-Augmented Generation](https://mlsanity.com/paper/2404.08189/) (2024)
- [ReLU2 Wins: Discovering Efficient Activation Functions for Sparse LLMs](https://mlsanity.com/paper/2402.03804/) (2024)
- [H-Neurons: On the Existence, Impact, and Origin of Hallucination-Associated Neurons in LLMs](https://mlsanity.com/paper/2512.01797/) (2025)
- [GraphCheck: Breaking Long-Term Text Barriers with Extracted Knowledge Graph-Powered Fact-Checking](https://mlsanity.com/paper/2502.16514/) (2025)
- [MedReflect: Teaching Medical LLMs to Self-Improve via Reflective Correction](https://mlsanity.com/paper/2510.03687/) (2025)
- [Do Hallucination Neurons Generalize? Evidence from Cross-Domain Transfer in LLMs](https://mlsanity.com/paper/2604.19765/) (2026)

## Abstract (arXiv)

Hallucination remains one of the central obstacles to deploying medical LLMs. Yet, even when hallucination can be detected, it is still unclear whether the internal representations associated with it can be used for control rather than detection alone. Using four open-source models across a suite of medical question-answering datasets, we show that a simple, carefully conditioned probe can reliably detect hallucination, with AUROC scores between 0.77 and 0.86 in our case. We further show that this signal is distributed and redundant rather than narrowly localized. Systematically selected neurons outperform random neurons only at very small subset sizes, whereas random subsets of a few hundred neurons recover nearly the full signal, and low-dimensional random projections preserve most of the detection performance. Beyond detection, we test whether this representation is causally actionable. Across 16 model--dataset combinations, our results reveal a sharp gap between decodability and controllability. The same internal structure that makes hallucination easy to detect does not translate into reliable neuron-level control. These findings show that medical hallucination seems to be readily visible in internal activations, but not easily corrected by steering the neurons most associated with it. More broadly, our results suggest that hallucination mitigation is not simply a matter of identifying the right neurons, and point to a deeper separation between what representations reveal and what they allow us to change.
