# Clarus: Coordinating Autonomous Research Agents toward Web-Scale Scientific Collaboration

arXiv: https://arxiv.org/abs/2606.30246 · HTML: https://mlsanity.com/paper/2606.30246/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Web, search, and research agents, one of 16 directions in LLM agents and tool use.
- Builds on 49 of its 79 references that are in the map.
- First posted on arXiv 29 Jun 2026.

## Placed in

- LLM agents and tool use / [Web, search, and research agents](https://mlsanity.com/agents/web-search-and-research-agents/)

## Builds on (most cited first, 30 of 49)

- [The AI Scientist: Towards Fully Automated Open-Ended Scientific Discovery](https://mlsanity.com/paper/2408.06292/) (2024)
- [AlphaEvolve: A coding agent for scientific and algorithmic discovery](https://mlsanity.com/paper/2506.13131/) (2025)
- [Counterfactual Multi-Agent Policy Gradients](https://mlsanity.com/paper/1705.08926/) (2017)
- [Value-Decomposition Networks For Cooperative Multi-Agent Learning](https://mlsanity.com/paper/1706.05296/) (2017)
- [Monotonic Value Function Factorisation for Deep Multi-Agent Reinforcement Learning](https://mlsanity.com/paper/2003.08839/) (2020)
- [Multi-Agent Collaboration Mechanisms: A Survey of LLMs](https://mlsanity.com/paper/2501.06322/) (2025)
- [Agent Laboratory: Using LLM Agents as Research Assistants](https://mlsanity.com/paper/2501.04227/) (2025)
- [The AI Scientist-v2: Workshop-Level Automated Scientific Discovery via Agentic Tree Search](https://mlsanity.com/paper/2504.08066/) (2025)
- [PaperBench: Evaluating AI's Ability to Replicate AI Research](https://mlsanity.com/paper/2504.01848/) (2025)
- [Agent-as-a-Judge: Evaluate Agents with Agents](https://mlsanity.com/paper/2410.10934/) (2024)
- [Towards End-to-End Automation of AI Research](https://mlsanity.com/paper/2606.15497/) (2026)
- [A survey of agent interoperability protocols: Model Context Protocol (MCP), Agent Communication Protocol (ACP), Agent-to-Agent Protocol (A2A), and Agent Network Protocol (ANP)](https://mlsanity.com/paper/2505.02279/) (2025)
- [A Survey on Trustworthy LLM Agents: Threats and Countermeasures](https://mlsanity.com/paper/2503.09648/) (2025)
- [A Survey of AI Agent Protocols](https://mlsanity.com/paper/2504.16736/) (2025)
- [Externalization in LLM Agents: A Unified Review of Memory, Skills, Protocols and Harness Engineering](https://mlsanity.com/paper/2604.08224/) (2026)
- [AgentRxiv: Towards Collaborative Autonomous Research](https://mlsanity.com/paper/2503.18102/) (2025)
- [Authenticated Delegation and Authorized AI Agents](https://mlsanity.com/paper/2501.09674/) (2025)
- [A Survey on LLM-based Multi-Agent System: Recent Advances and New Frontiers in Application](https://mlsanity.com/paper/2412.17481/) (2024)
- [Agentic Web: Weaving the Next Web with AI Agents](https://mlsanity.com/paper/2507.21206/) (2025)
- [Multi-Agent Coordination across Diverse Applications: A Survey](https://mlsanity.com/paper/2502.14743/) (2025)
- [Agent-Oriented Planning in Multi-Agent Systems](https://mlsanity.com/paper/2410.02189/) (2024)
- [PROV-AGENT: Unified Provenance for Tracking AI Agent Interactions in Agentic Workflows](https://mlsanity.com/paper/2508.02866/) (2025)
- [A Novel Zero-Trust Identity Framework for Agentic AI: Decentralized Authentication and Fine-Grained Access Control](https://mlsanity.com/paper/2505.19301/) (2025)
- [AutoResearchClaw: Self-Reinforcing Autonomous Research with Human-AI Collaboration](https://mlsanity.com/paper/2605.20025/) (2026)
- [Packaging research artefacts with RO-Crate](https://mlsanity.com/paper/2108.06503/) (2021)
- [Agent Name Service (ANS): A Universal Directory for Secure AI Agent Discovery and Interoperability](https://mlsanity.com/paper/2505.10609/) (2025)
- [AutoSOTA: An End-to-End Automated Research System for State-of-the-Art AI Model Discovery](https://mlsanity.com/paper/2604.05550/) (2026)
- [REPRO-Bench: Can Agentic AI Systems Assess the Reproducibility of Social Science Research?](https://mlsanity.com/paper/2507.18901/) (2025)
- [Leveraging Large Language Models for Effective and Explainable Multi-Agent Credit Assignment](https://mlsanity.com/paper/2502.16863/) (2025)
- [A Vision for Auto Research with LLM Agents](https://mlsanity.com/paper/2504.18765/) (2025)

## Abstract (arXiv)

Existing autonomous research agents can support parts of the research process, but most systems still treat research as either an isolated assistant task or a closed workflow. Therefore, autonomous science needs a collaboration infrastructure that coordinates projects, agents, and digital and physical resources. We identify this as a shift from code-centered execution loops to research-oriented collaboration processes, where questions, evidence, participants, and resources must be coordinated under uncertainty. In this framing, an agent may be an AI system, a human researcher, a team, a laboratory, or an organization-backed participant. To this end, we present Clarus, a collaboration infrastructure for coordinating autonomous research agents toward web-scale scientific collaboration. Clarus reformulates research as an open, auditable, attributable, and resource-aware multi-phase collaboration process. It defines a minimal project-agent-resource object model and organizes scientific collaboration through four layers including Research Application, Digital Collaboration, Physical Substrate, and Physical World. Core modules are implemented as pluggable mechanisms, allowing Clarus to adapt to task risk, collaboration structure, and resource constraints. Through a controlled paper-generation case study, we show that Clarus can organize a research goal into a traceable, reviewable, attributable, and accumulative collaboration network across phases, tasks, and participants. Together, the object model, collaboration protocol, trust mechanisms, and prototype validation provide an initial foundation for open research networks. Clarus is now available at clarus.holosai.io.