# DEEPMED Search: An Open-Source Agentic Platform for Medical Deep Research with Introspective Verification

arXiv: https://arxiv.org/abs/2606.29746 · HTML: https://mlsanity.com/paper/2606.29746/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use.
- Builds on 14 of its 20 references that are in the map.
- First posted on arXiv 29 Jun 2026.

## Placed in

- LLM agents and tool use / [Medical and scientific domain agents](https://mlsanity.com/agents/medical-and-scientific-domain-agents/)

## Builds on (most cited first, 14 of 14)

- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [ReAct: Synergizing Reasoning and Acting in Language Models](https://mlsanity.com/paper/2210.03629/) (2022)
- [Dense Passage Retrieval for Open-Domain Question Answering](https://mlsanity.com/paper/2004.04906/) (2020)
- [Survey of Hallucination in Natural Language Generation](https://mlsanity.com/paper/2202.03629/) (2022)
- [Improving Factuality and Reasoning in Language Models through Multiagent Debate](https://mlsanity.com/paper/2305.14325/) (2023)
- [Leveraging Passage Retrieval with Generative Models for Open Domain Question Answering](https://mlsanity.com/paper/2007.01282/) (2020)
- [When Not to Trust Language Models: Investigating Effectiveness of Parametric and Non-Parametric Memories](https://mlsanity.com/paper/2212.10511/) (2022)
- [ChatEval: Towards Better LLM-based Evaluators through Multi-Agent Debate](https://mlsanity.com/paper/2308.07201/) (2023)
- [Large Language Models Struggle to Learn Long-Tail Knowledge](https://mlsanity.com/paper/2211.08411/) (2022)
- [Causal Reasoning and Large Language Models: Opening a New Frontier for Causality](https://mlsanity.com/paper/2305.00050/) (2023)
- [Benchmarking Retrieval-Augmented Generation for Medicine](https://mlsanity.com/paper/2402.13178/) (2024)
- [MedAgent-Pro: Towards Evidence-based Multi-modal Medical Diagnosis via Reasoning Agentic Workflow](https://mlsanity.com/paper/2503.18968/) (2025)
- [Quantifying the Reasoning Abilities of LLMs on Real-world Clinical Cases](https://mlsanity.com/paper/2503.04691/) (2025)
- [Toward Robust RALMs: Revealing the Impact of Imperfect Retrieval on Retrieval-Augmented Language Models](https://mlsanity.com/paper/2410.15107/) (2024)

## Abstract (arXiv)

Navigating the deluge of heterogeneous medical data, from academic literature (PubMed) to clinical guidelines (Web) and private knowledge bases, remains a critical bottleneck for evidence-based medicine. While commercial black-box tools lack transparency, standard open-source RAG implementations frequently suffer from reasoning drift when handling complex, long-tail queries. We present DEEPMED Search, a fully open-source, agentic platform designed for transparent medical deep research. Built on a high-performance Next.js architecture, DEEPMED Search features a source-adaptive router that autonomously dispatches sub-queries to PubMed, web search, or local graph-based knowledge bases based on information density. Crucially, the platform integrates an introspective verification module, powered by a causal-consistent multi-agent debate framework, to validate retrieved evidence against diagnostic logic before synthesis. To demonstrate its robustness, we showcase DEEPMED Search's ability to autonomously decompose high-difficulty rare disease queries, filter out confounding noise, and generate structured, citation-backed research reports in minutes. By open-sourcing this software, we provide the community with a robust infrastructure to democratize access to trustworthy, glass-box medical reasoning in research and prototyping settings.