# A Deep Multiscale Neural Network for Accurate Neurological Disorder Detection from MRI Scans and Real-Time Web Deployment

arXiv: https://arxiv.org/abs/2606.29106 · HTML: https://mlsanity.com/paper/2606.29106/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 4 of its 36 references that are in the map.
- First posted on arXiv 27 Jun 2026.

## Builds on (most cited first, 4 of 4)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [One-shot domain adaptation in multiple sclerosis lesion segmentation using convolutional neural networks](https://mlsanity.com/paper/1805.12415/) (2018)
- [Leveraging Deep Learning and Xception Architecture for High-Accuracy MRI Classification in Alzheimer Diagnosis](https://mlsanity.com/paper/2403.16212/) (2024)

## Abstract (arXiv)

Neurological disorders involve diverse pathologies of the brain and nervous system, making early and accurate detection essential. While many deep CNNs have been developed for MRI-based classification of neurological disorders, most are optimized for binary tasks and often fail to capture the multi-class features needed to distinguish subtle anatomical differences across conditions. This study proposes the Enhanced Neurological Disorder Detection Network (End-Net) for multi-class MRI classification of neurological disorders. End-Net includes 24 convolutional layers, beginning with convolutional blocks followed by 21 optimized inception modules. These modules extract multiscale features via parallel 1 x 1, 3 x 3, and factorized 5 x 5 convolutional branches, along with max pooling, enabling the model to capture complementary texture, edge, shape, and contextual information. A global average pooling head, compact fully connected classifier, and dropout reduce parameters, limit overfitting, and improve robustness. End-Net was evaluated on the Multi-Class Neurological Disorder dataset, comprising MRI scans from patients with Alzheimer's disease, brain tumors, multiple sclerosis, and healthy controls. Severe class imbalance was addressed by augmenting minority classes with WGAN-GP and randomly undersampling the majority class. The results show that End-Net outperforms existing architectures in both accuracy and generalization. The model is also integrated into an online system for real-time web-based inference and accessibility.