# M3 QuestionIng: Multi-modal Multi-span Medical Question Answering

arXiv: https://arxiv.org/abs/2606.28329 · HTML: https://mlsanity.com/paper/2606.28329/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 42 of its 67 references that are in the map.
- First posted on arXiv 19 May 2026.

## Builds on (most cited first, 30 of 42)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [RoBERTa: A Robustly Optimized BERT Pretraining Approach](https://mlsanity.com/paper/1907.11692/) (2019)
- [Emerging Properties in Self-Supervised Vision Transformers](https://mlsanity.com/paper/2104.14294/) (2021)
- [BLIP-2: Bootstrapping Language-Image Pre-training with Frozen Image Encoders and Large Language Models](https://mlsanity.com/paper/2301.12597/) (2023)
- [Longformer: The Long-Document Transformer](https://mlsanity.com/paper/2004.05150/) (2020)
- [XLNet: Generalized Autoregressive Pretraining for Language Understanding](https://mlsanity.com/paper/1906.08237/) (2019)
- [CLIPScore: A Reference-free Evaluation Metric for Image Captioning](https://mlsanity.com/paper/2104.08718/) (2021)
- [BioBERT: a pre-trained biomedical language representation model for biomedical text mining](https://mlsanity.com/paper/1901.08746/) (2019)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [Domain-Specific Language Model Pretraining for Biomedical Natural Language Processing](https://mlsanity.com/paper/2007.15779/) (2020)
- [MedCLIP: Contrastive Learning from Unpaired Medical Images and Text](https://mlsanity.com/paper/2210.10163/) (2022)
- [ClinicalBERT: Modeling Clinical Notes and Predicting Hospital Readmission](https://mlsanity.com/paper/1904.05342/) (2019)
- [PathVQA: 30000+ Questions for Medical Visual Question Answering](https://mlsanity.com/paper/2003.10286/) (2020)
- [SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answering](https://mlsanity.com/paper/2102.09542/) (2021)
- [VLM2Vec: Training Vision-Language Models for Massive Multimodal Embedding Tasks](https://mlsanity.com/paper/2410.05160/) (2024)
- [PMC-CLIP: Contrastive Language-Image Pre-training using Biomedical Documents](https://mlsanity.com/paper/2303.07240/) (2023)
- [Learning to Exploit Temporal Structure for Biomedical Vision-Language Processing](https://mlsanity.com/paper/2301.04558/) (2023)
- [MultiModalQA: Complex Question Answering over Text, Tables and Images](https://mlsanity.com/paper/2104.06039/) (2021)
- [Sparse Sequence-to-Sequence Models](https://mlsanity.com/paper/1905.05702/) (2019)
- [MM-Embed: Universal Multimodal Retrieval with Multimodal LLMs](https://mlsanity.com/paper/2411.02571/) (2024)
- [A Question-Entailment Approach to Question Answering](https://mlsanity.com/paper/1901.08079/) (2019)
- [HealthGPT: A Medical Large Vision-Language Model for Unifying Comprehension and Generation via Heterogeneous Knowledge Adaptation](https://mlsanity.com/paper/2502.09838/) (2025)
- [MMed-RAG: Versatile Multimodal RAG System for Medical Vision Language Models](https://mlsanity.com/paper/2410.13085/) (2024)
- [TANDA: Transfer and Adapt Pre-Trained Transformer Models for Answer Sentence Selection](https://mlsanity.com/paper/1911.04118/) (2019)
- [EHRXQA: A Multi-Modal Question Answering Dataset for Electronic Health Records with Chest X-ray Images](https://mlsanity.com/paper/2310.18652/) (2023)
- [Towards a clinically accessible radiology foundation model: open-access and lightweight, with automated evaluation](https://mlsanity.com/paper/2403.08002/) (2024)
- [Med-MoE: Mixture of Domain-Specific Experts for Lightweight Medical Vision-Language Models](https://mlsanity.com/paper/2404.10237/) (2024)
- [UniMed-CLIP: Towards a Unified Image-Text Pretraining Paradigm for Diverse Medical Imaging Modalities](https://mlsanity.com/paper/2412.10372/) (2024)

## Abstract (arXiv)

The growing adoption of AI in healthcare, particularly in preventive care, highlights the critical need for accessibility and precision in Medical Question Answering (MedQA). In recent years, significant efforts have been made to develop multi-span medical question-answering systems, where the answer to a query may span multiple sections or paragraphs of a source document. However, existing systems fall short of aligning with real-world scenarios, where source documents often include both textual and visual content, requiring answers to incorporate images for better comprehension. To address this gap, we propose M3QAFrame, a multi-modal, multi-span medical question-answering framework that leverages visual cues to enhance the generation of comprehensive answers drawn from diverse textual and visual spans. The model takes the context, query, and images as input and outputs an answer containing both textual answers and relevant images. The text and image embeddings are processed using a transformer-based architecture to determine the sentence and image relevance. We curate a multi-modal, multi-span medical question-answering (M3 QuestionIng) dataset containing queries, medical contexts, associated medical images, and extractive answers. Additionally, each query-answer pair is labeled with user intent and query type to enhance query and context comprehension. Extensive experiments show that our approach consistently outperforms existing methods across various evaluation metrics.