# Latent Diffusion Posterior Sampling with Surrogate Likelihood Guidance for PDE Inverse Problems

arXiv: https://arxiv.org/abs/2606.26592 · HTML: https://mlsanity.com/paper/2606.26592/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Placed in Flow matching, time series and science, one of 14 directions in Diffusion models.
- Builds on 11 of its 15 references that are in the map.
- First posted on arXiv 25 Jun 2026.

## Placed in

- Diffusion models / [Flow matching, time series and science](https://mlsanity.com/diffusion/flow-matching-time-series-and-science/)

## Builds on (most cited first, 11 of 11)

- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Denoising Diffusion Implicit Models](https://mlsanity.com/paper/2010.02502/) (2020)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Zero-Shot Text-to-Image Generation](https://mlsanity.com/paper/2102.12092/) (2021)
- [Taming Transformers for High-Resolution Image Synthesis](https://mlsanity.com/paper/2012.09841/) (2020)
- [Diffusion Posterior Sampling for General Noisy Inverse Problems](https://mlsanity.com/paper/2209.14687/) (2022)
- [Denoising Diffusion Restoration Models](https://mlsanity.com/paper/2201.11793/) (2022)
- [Diffusion State-Guided Projected Gradient for Inverse Problems](https://mlsanity.com/paper/2410.03463/) (2024)
- [VAE-DNN: Energy-Efficient Trainable-by-Parts Surrogate Model For Parametric Partial Differential Equations](https://mlsanity.com/paper/2508.03839/) (2025)
- [SURGIN: SURrogate-guided Generative INversion for subsurface multiphase flow with quantified uncertainty](https://mlsanity.com/paper/2509.13189/) (2025)

## Built on by (most cited first, 1 of 1)

- [LatentFlow: A General Framework for Conditioning Stochastic Processes](https://mlsanity.com/paper/2607.12922/) (2026)

## Abstract (arXiv)

We propose latent-space diffusion posterior sampling (L-DPS), an approximate Bayesian framework for high-dimensional inverse problems governed by partial differential equations (PDEs). The method addresses three challenges in PDE-constrained inversion: implicit sample-based priors without tractable densities, high-dimensional spatially distributed parameters, and the high cost of repeated forward-model evaluations during posterior sampling. L-DPS combines a variational autoencoder, an unconditional latent diffusion model, diffusion posterior sampling, and a differentiable neural surrogate. The VAE maps the parameter field to a lower-dimensional latent space, the diffusion model learns an implicit prior score in this latent space, and DPS combines this learned prior with likelihood-based guidance. The likelihood gradient is evaluated through the decoder-surrogate composition, avoiding repeated calls to the full numerical PDE solver. We evaluate the method on an inverse Darcy flow problem with an unknown spatially distributed permeability field inferred from sparse and noisy pressure observations. L-DPS produces accurate and robust inverse solutions, reduces inference cost relative to full-space DPS, and outperforms amortized inverse baselines such as conditional latent diffusion and inverse FNO in sparse and noisy regimes. We further compare L-DPS with a KLE-MAP baseline and study mixed-prior generalization and the sensitivity of inversion accuracy to surrogate forward-model error.
