# Revealing Mammographic Phenotypes in Deep Learning Breast Cancer Risk Models

arXiv: https://arxiv.org/abs/2606.26431 · HTML: https://mlsanity.com/paper/2606.26431/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 0 of its 9 references that are in the map.
- First posted on arXiv 24 Jun 2026.

## Abstract (arXiv)

Mammogram-based deep learning models have improved breast cancer risk prediction, but the learned imaging patterns remain underexplored. Existing interpretability methods rely on single-image saliency maps, failing to identify recurring mammographic phenotypes across large patient cohorts. By clustering patch embeddings from a pre-trained model, Mirai, we isolate recurring phenotypes linked to 5-year cancer risk. Analyses show risk-increasing phenotypes capture complex structures (e.g., dense tissue, microcalcifications) and shortcut artifacts (e.g., clips). These phenotypes correlate strongly with older age and higher BI-RADS density. Our framework connects tissue patterns to AI risk scores, revealing clinical signatures and potential latent model confounders.