# One Year Later...The Harms Persist, But So Do We!

arXiv: https://arxiv.org/abs/2606.23884 · HTML: https://mlsanity.com/paper/2606.23884/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Safety alignment, refusal and guardrails, one of 12 directions in LLM safety and security.
- Builds on 26 of its 57 references that are in the map.
- First posted on arXiv 22 Jun 2026.

## Placed in

- LLM safety and security / [Safety alignment, refusal and guardrails](https://mlsanity.com/safety/safety-alignment-refusal-and-guardrails/)

## Builds on (most cited first, 26 of 26)

- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [Jailbroken: How Does LLM Safety Training Fail?](https://mlsanity.com/paper/2307.02483/) (2023)
- [HarmBench: A Standardized Evaluation Framework for Automated Red Teaming and Robust Refusal](https://mlsanity.com/paper/2402.04249/) (2024)
- [Towards Understanding Sycophancy in Language Models](https://mlsanity.com/paper/2310.13548/) (2023)
- [Red Teaming Language Models with Language Models](https://mlsanity.com/paper/2202.03286/) (2022)
- [Red Teaming Language Models to Reduce Harms: Methods, Scaling Behaviors, and Lessons Learned](https://mlsanity.com/paper/2209.07858/) (2022)
- [Jailbreaking ChatGPT via Prompt Engineering: An Empirical Study](https://mlsanity.com/paper/2305.13860/) (2023)
- ["Do Anything Now": Characterizing and Evaluating In-The-Wild Jailbreak Prompts on Large Language Models](https://mlsanity.com/paper/2308.03825/) (2023)
- [Prometheus 2: An Open Source Language Model Specialized in Evaluating Other Language Models](https://mlsanity.com/paper/2405.01535/) (2024)
- [A StrongREJECT for Empty Jailbreaks](https://mlsanity.com/paper/2402.10260/) (2024)
- [JudgeLM: Fine-tuned Large Language Models are Scalable Judges](https://mlsanity.com/paper/2310.17631/) (2023)
- [Multi-step Jailbreaking Privacy Attacks on ChatGPT](https://mlsanity.com/paper/2304.05197/) (2023)
- [PandaLM: An Automatic Evaluation Benchmark for LLM Instruction Tuning Optimization](https://mlsanity.com/paper/2306.05087/) (2023)
- [SORRY-Bench: Systematically Evaluating Large Language Model Safety Refusal](https://mlsanity.com/paper/2406.14598/) (2024)
- [Generative Judge for Evaluating Alignment](https://mlsanity.com/paper/2310.05470/) (2023)
- [MART: Improving LLM Safety with Multi-round Automatic Red-Teaming](https://mlsanity.com/paper/2311.07689/) (2023)
- [BadChain: Backdoor Chain-of-Thought Prompting for Large Language Models](https://mlsanity.com/paper/2401.12242/) (2024)
- [The opportunities and risks of large language models in mental health](https://mlsanity.com/paper/2403.14814/) (2024)
- [Benefits and Harms of Large Language Models in Digital Mental Health](https://mlsanity.com/paper/2311.14693/) (2023)
- [LLM-empowered Chatbots for Psychiatrist and Patient Simulation: Application and Evaluation](https://mlsanity.com/paper/2305.13614/) (2023)
- [Large Language Models in Mental Health Care: a Scoping Review](https://mlsanity.com/paper/2401.02984/) (2024)
- [Towards Safe AI Clinicians: A Comprehensive Study on Large Language Model Jailbreaking in Healthcare](https://mlsanity.com/paper/2501.18632/) (2025)
- [Assessing the Quality of Mental Health Support in LLM Responses through Multi-Attribute Human Evaluation](https://mlsanity.com/paper/2601.18630/) (2026)
- [Independent Clinical Evaluation of General-Purpose LLM Responses to Signals of Suicide Risk](https://mlsanity.com/paper/2510.27521/) (2025)
- [Differential Harm Propensity in Personalized LLM Agents: The Curious Case of Mental Health Disclosure](https://mlsanity.com/paper/2603.16734/) (2026)

## Abstract (arXiv)

General-purpose large language models (LLMs) are increasingly used for mental health-related conversations, yet safety guardrails remain inadequate and inconsistent across clinical conditions. This study evaluates eight proprietary LLMs across 16 DSM-5 conditions using four adversarial attack variants, introducing an eight-dimension harm taxonomy and a multi-dimensional evaluation framework. Results show that safeguards hold reliably only for suicide and self-harm, while conditions such as eating disorders, substance use disorder, and major depressive disorder exhibit failure rates of up to 100%. We argue that ethical design and deployment of these LLMs demand clearly defined harm categories across clinical conditions and implementation of safeguards accordingly. Until such safeguards are in place, these models pose significant risks to vulnerable populations, making their growing integration into publicly available settings (e.g., schools, search engines, and consumer chatbots) are particularly concerning.
