# Efficient Multimodal Clinical Question Answering for Pulmonary Embolism Risk Assessment

arXiv: https://arxiv.org/abs/2606.22442 · HTML: https://mlsanity.com/paper/2606.22442/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 7 of its 25 references that are in the map.
- First posted on arXiv 21 Jun 2026.

## Builds on (most cited first, 7 of 7)

- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answering](https://mlsanity.com/paper/2102.09542/) (2021)
- [Med-Flamingo: a Multimodal Medical Few-shot Learner](https://mlsanity.com/paper/2307.15189/) (2023)
- [Towards Generalist Biomedical AI](https://mlsanity.com/paper/2307.14334/) (2023)
- [RadFusion: Benchmarking Performance and Fairness for Multimodal Pulmonary Embolism Detection from CT and EHR](https://mlsanity.com/paper/2111.11665/) (2021)
- [INSPECT: A Multimodal Dataset for Pulmonary Embolism Diagnosis and Prognosis](https://mlsanity.com/paper/2311.10798/) (2023)
- [Unified Supervision For Vision-Language Modeling in 3D Computed Tomography](https://mlsanity.com/paper/2509.01554/) (2025)

## Abstract (arXiv)

Pulmonary embolism (PE) is a high risk cardiopulmonary condition whose management requires both timely diagnosis and reliable assessment of future clinical risk. Because PE care routinely combines computed tomography pulmonary angiography (CTPA), radiology interpretation, and longitudinal electronic health record (EHR) evidence, it provides a clinically meaningful setting for evaluating compact multimodal language models. In this work, we build a benchmark using efficient multimodal large language models (MLLMs) on INSPECT, a multimodal PE dataset containing 23,248 CTPA studies from 19,402 patients. We formulate eight diagnostic and prognostic tasks as structured clinical question answering problems and evaluate on typical efficient MLLMs under CTPA-Only, EHR-Only, and CTPA+EHR settings with zero-shot and few-shot prompting. Results show that Gemma4 E4B and Gemma4 E2B perform more strongly when EHR evidence is available, especially under CTPA+EHR input. Task level analysis further shows that PE diagnosis achieves higher performance than prognostic tasks, particularly readmission prediction. These observations suggest that compact multimodal models have the great potential in early stage PE risk detection and explanation.
