# Cloze: An Open Research Platform for Studying Human-AI Conversations in Mental Health Contexts

arXiv: https://arxiv.org/abs/2606.15033 · HTML: https://mlsanity.com/paper/2606.15033/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 5 of its 19 references that are in the map.
- First posted on arXiv 13 Jun 2026.

## Builds on (most cited first, 5 of 5)

- [Expressing stigma and inappropriate responses prevents LLMs from safely replacing mental health providers](https://mlsanity.com/paper/2504.18412/) (2025)
- [Exploring User Security and Privacy Attitudes and Concerns Toward the Use of General-Purpose LLM Chatbots for Mental Health](https://mlsanity.com/paper/2507.10695/) (2025)
- [MindBenchAI: An Actionable Platform to Evaluate the Profile and Performance of Large Language Models in a Mental Healthcare Context](https://mlsanity.com/paper/2510.13812/) (2025)
- [Customizable LLM-Powered Chatbot for Behavioral Science Research](https://mlsanity.com/paper/2501.05541/) (2025)
- [Facilitating the Integration of LLMs Into Online Experiments With Simple Chat](https://mlsanity.com/paper/2511.19123/) (2025)

## Abstract (arXiv)

Cloze is an open-source web platform for conducting controlled, monitored studies of human-AI conversation in mental health research contexts. Consumer large language model (LLM) products such as ChatGPT, Claude, and Gemini are built for individual productivity, and offer researchers little experimental control, inconsistent data export, and no shared safety scaffolding that holds across providers. Cloze gives research teams a single environment in which they configure which models participants converse with, how the AI is instructed, how conversations are scheduled over time, and which safety constraints apply unconditionally, while every message is captured with full provenance (model version, prompt configuration, timing). The platform currently supports OpenAI, Anthropic, Google, and locally hosted open-weight models served through Ollama behind a unified interface, and runs in the cloud or fully on premises so that participant data need never leave an institution. Cloze is research infrastructure for building an evidence base on human-AI interaction in mental health contexts. It is not a therapeutic product.