# LLM-Powered Personalized Glycemic Assessment in Type 2 Diabetes with Wearable Sensor Data

arXiv: https://arxiv.org/abs/2606.12699 · HTML: https://mlsanity.com/paper/2606.12699/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 17 of its 43 references that are in the map.
- First posted on arXiv 10 Jun 2026.

## Builds on (most cited first, 17 of 17)

- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [Large Language Models are Zero-Shot Reasoners](https://mlsanity.com/paper/2205.11916/) (2022)
- [Mistral 7B](https://mlsanity.com/paper/2310.06825/) (2023)
- [A Time Series is Worth 64 Words: Long-term Forecasting with Transformers](https://mlsanity.com/paper/2211.14730/) (2022)
- [Gemma 2: Improving Open Language Models at a Practical Size](https://mlsanity.com/paper/2408.00118/) (2024)
- [iTransformer: Inverted Transformers Are Effective for Time Series Forecasting](https://mlsanity.com/paper/2310.06625/) (2023)
- [Are Language Models Actually Useful for Time Series Forecasting?](https://mlsanity.com/paper/2406.16964/) (2024)
- [Navigating Text-To-Image Customization: From LyCORIS Fine-Tuning to Model Evaluation](https://mlsanity.com/paper/2309.14859/) (2023)
- [Med42-v2: A Suite of Clinical LLMs](https://mlsanity.com/paper/2408.06142/) (2024)
- [Mental-LLM: Leveraging Large Language Models for Mental Health Prediction via Online Text Data](https://mlsanity.com/paper/2307.14385/) (2023)
- [Health-LLM: Large Language Models for Health Prediction via Wearable Sensor Data](https://mlsanity.com/paper/2401.06866/) (2024)
- [Empowering Time Series Analysis with Large Language Models: A Survey](https://mlsanity.com/paper/2402.03182/) (2024)
- [SensorLM: Learning the Language of Wearable Sensors](https://mlsanity.com/paper/2506.09108/) (2025)
- [DM-Bench: Benchmarking LLMs for Personalized Decision Making in Diabetes Management](https://mlsanity.com/paper/2510.00038/) (2025)
- [FedKRSO: Communication and Memory Efficient Federated Fine-Tuning of Large Language Models](https://mlsanity.com/paper/2602.03019/) (2026)

## Built on by (most cited first, 1 of 1)

- [It's All in the Way You Say It: The Role of Information Representation in LLM-Based Glycemic-Event Prediction](https://mlsanity.com/paper/2609.08772/) (2026)

## Abstract (arXiv)

Type 2 Diabetes (T2D) poses an increasing global health threat, demanding effective glycemic assessment to support personalized and improved diabetes care. Wearable sensors such as continuous glucose monitors (CGM) and fitness trackers offer many valuable insights for glycemic assessment. However, effectively analyzing these data requires integration with essential individual-level context. Existing methods are often based on traditional machine learning (ML) and rely primarily on historical blood glucose measurements and overlook personalized information, which limits their performance across diverse diabetes populations. Recent advances in large language models (LLMs) have demonstrated their ability to integrate diverse data modalities while modeling sequential dependencies, motivating the exploration of their potential for personalized glycemic assessment. In this paper, we propose GlyLLM, an LLM-powered framework for modeling CGM-based glycemic dynamics through the integration of wearable sensor data and structured metadata. GlyLLM can leverage the extensive prior knowledge of pre-trained LLMs and achieve sensor-text semantic abstraction at decision time. Experiments on two related tasks on the AI-READI dataset demonstrate that our model outperforms traditional ML methods by an average of 13.66% in Root Mean Squared Error (RMSE) for glucose forecasting and 13.08% in Area Under the Receiver Operating Characteristic (AUROC) for diabetes categorization. Additionally, our ablation study shows that diabetes surveys and biometric tests are more critical than other health information for glycemic assessment. Our work presents a promising step toward harnessing the power of LLMs to advance personalized glycemic assessment in T2D care.
