# A robust PPG foundation model using multimodal physiological supervision

arXiv: https://arxiv.org/abs/2606.07365 · HTML: https://mlsanity.com/paper/2606.07365/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 26 of its 62 references that are in the map.
- First posted on arXiv 5 Jun 2026.

## Builds on (most cited first, 26 of 26)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Masked Autoencoders Are Scalable Vision Learners](https://mlsanity.com/paper/2111.06377/) (2021)
- [On the Opportunities and Risks of Foundation Models](https://mlsanity.com/paper/2108.07258/) (2021)
- [Scaling Up Visual and Vision-Language Representation Learning With Noisy Text Supervision](https://mlsanity.com/paper/2102.05918/) (2021)
- [UMAP: Uniform Manifold Approximation and Projection for Dimension Reduction](https://mlsanity.com/paper/1802.03426/) (2018)
- [A Time Series is Worth 64 Words: Long-term Forecasting with Transformers](https://mlsanity.com/paper/2211.14730/) (2022)
- [Chronos: Learning the Language of Time Series](https://mlsanity.com/paper/2403.07815/) (2024)
- [MOMENT: A Family of Open Time-series Foundation Models](https://mlsanity.com/paper/2402.03885/) (2024)
- [Multimodal Foundation Models: From Specialists to General-Purpose Assistants](https://mlsanity.com/paper/2309.10020/) (2023)
- [Unsupervised Representation Learning for Time Series with Temporal Neighborhood Coding](https://mlsanity.com/paper/2106.00750/) (2021)
- [BENDR: using transformers and a contrastive self-supervised learning task to learn from massive amounts of EEG data](https://mlsanity.com/paper/2101.12037/) (2021)
- [SimMTM: A Simple Pre-Training Framework for Masked Time-Series Modeling](https://mlsanity.com/paper/2302.00861/) (2023)
- [Large-scale Training of Foundation Models for Wearable Biosignals](https://mlsanity.com/paper/2312.05409/) (2023)
- [Rank-N-Contrast: Learning Continuous Representations for Regression](https://mlsanity.com/paper/2210.01189/) (2022)
- [PaPaGei: Open Foundation Models for Optical Physiological Signals](https://mlsanity.com/paper/2410.20542/) (2024)
- [MAEEG: Masked Auto-encoder for EEG Representation Learning](https://mlsanity.com/paper/2211.02625/) (2022)
- [SensorLM: Learning the Language of Wearable Sensors](https://mlsanity.com/paper/2506.09108/) (2025)
- [Pulse-PPG: An Open-Source Field-Trained PPG Foundation Model for Wearable Applications Across Lab and Field Settings](https://mlsanity.com/paper/2502.01108/) (2025)
- [Frequency-Aware Masked Autoencoders for Multimodal Pretraining on Biosignals](https://mlsanity.com/paper/2309.05927/) (2023)
- [REBAR: Retrieval-Based Reconstruction for Time-series Contrastive Learning](https://mlsanity.com/paper/2311.00519/) (2023)
- [RelCon: Relative Contrastive Learning for a Motion Foundation Model for Wearable Data](https://mlsanity.com/paper/2411.18822/) (2024)
- [Wearable Accelerometer Foundation Models for Health via Knowledge Distillation](https://mlsanity.com/paper/2412.11276/) (2024)
- [WildPPG: A Real-World PPG Dataset of Long Continuous Recordings](https://mlsanity.com/paper/2412.17540/) (2024)
- [Promoting cross-modal representations to improve multimodal foundation models for physiological signals](https://mlsanity.com/paper/2410.16424/) (2024)
- [CiTrus: Squeezing Extra Performance out of Low-data Bio-signal Transfer Learning](https://mlsanity.com/paper/2412.11695/) (2024)
- [A General Framework for Generative Self-supervised Learning in Non-invasive Estimation of Physiological Parameters Using Photoplethysmography](https://mlsanity.com/paper/2604.22780/) (2026)

## Built on by (most cited first, 3 of 3)

- [When Derived Measurements Mislead: Quantifying and Mitigating LLM Over-Trust with Privileged-Modality Reliability Evidence](https://mlsanity.com/paper/2607.28421/) (2026)
- [PPG-LM: A Photoplethysmography-Language Model with Multi-Level Clinical Alignment](https://mlsanity.com/paper/2609.33516/) (2026)
- [RAE-PPG: Duration-Grounded Retain-and-Extend Pretraining for PPG Foundation Models](https://mlsanity.com/paper/2609.36794/) (2026)

## Abstract (arXiv)

Photoplethysmography (PPG), a non-invasive measure of changes in blood volume, is widely used in both wearable devices and clinical settings. Recent PPG foundation models either use open-source ICU datasets with pretraining paradigms that require curated data and thus complicate generalization to field-like data, or use closed-source field-like PPG data. In contrast, we propose a PPG foundation model that does not require high-quality or field-like pretraining data, and instead leverages accompanying electrocardiogram and respiratory signals in ICU datasets to select contrastive samples during pretraining. Our approach allows the model to retain and learn from noisy PPG segments, improving robustness at inference. Our model, pretrained on 3x fewer subjects than existing state-of-the-art approaches, achieves performance improvements on 14 out of 15 diverse downstream tasks, including field-like daily activity and heart rate prediction. Our results demonstrate that multimodal supervision can integrate complementary physiological information to improve the robustness of PPG foundation models and enhance their generalization to consumer-grade data.