# AgensFlow: A Coordination-Policy Substrate for Multi-Agent Systems

arXiv: https://arxiv.org/abs/2605.27466 · HTML: https://mlsanity.com/paper/2605.27466/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in General LLM agent frameworks and benchmarks, one of 16 directions in LLM agents and tool use.
- Builds on 20 of its 29 references that are in the map.
- First posted on arXiv 26 May 2026.

## Placed in

- LLM agents and tool use / [General LLM agent frameworks and benchmarks](https://mlsanity.com/agents/general-llm-agent-frameworks-and-benchmarks/)

## Builds on (most cited first, 20 of 20)

- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [ReAct: Synergizing Reasoning and Acting in Language Models](https://mlsanity.com/paper/2210.03629/) (2022)
- [Toolformer: Language Models Can Teach Themselves to Use Tools](https://mlsanity.com/paper/2302.04761/) (2023)
- [A Survey on Large Language Model based Autonomous Agents](https://mlsanity.com/paper/2308.11432/) (2023)
- [AutoGen: Enabling Next-Gen LLM Applications via Multi-Agent Conversation](https://mlsanity.com/paper/2308.08155/) (2023)
- [SWE-agent: Agent-Computer Interfaces Enable Automated Software Engineering](https://mlsanity.com/paper/2405.15793/) (2024)
- [CAMEL: Communicative Agents for "Mind" Exploration of Large Language Model Society](https://mlsanity.com/paper/2303.17760/) (2023)
- [The AI Scientist-v2: Workshop-Level Automated Scientific Discovery via Agentic Tree Search](https://mlsanity.com/paper/2504.08066/) (2025)
- [TheAgentCompany: Benchmarking LLM Agents on Consequential Real World Tasks](https://mlsanity.com/paper/2412.14161/) (2024)
- [SkillsBench: Benchmarking How Well Agent Skills Work Across Diverse Tasks](https://mlsanity.com/paper/2602.12670/) (2026)
- [Recurrent Independent Mechanisms](https://mlsanity.com/paper/1909.10893/) (2019)
- [Towards a Science of Scaling Agent Systems](https://mlsanity.com/paper/2512.08296/) (2025)
- [Kosmos: An AI Scientist for Autonomous Discovery](https://mlsanity.com/paper/2511.02824/) (2025)
- [Agent Skills: A Data-Driven Analysis of Claude Skills for Extending Large Language Model Functionality](https://mlsanity.com/paper/2602.08004/) (2026)
- [Health-LLM: Large Language Models for Health Prediction via Wearable Sensor Data](https://mlsanity.com/paper/2401.06866/) (2024)
- [Finance Agent Benchmark: Benchmarking LLMs on Real-world Financial Research Tasks](https://mlsanity.com/paper/2508.00828/) (2025)
- [CodeAgent: Autonomous Communicative Agents for Code Review](https://mlsanity.com/paper/2402.02172/) (2024)
- [Agentic AI Systems Applied to tasks in Financial Services: Modeling and model risk management crews](https://mlsanity.com/paper/2502.05439/) (2025)
- [MedMemoryBench: Benchmarking Agent Memory in Personalized Healthcare](https://mlsanity.com/paper/2605.11814/) (2026)
- [Dynamic and Context-Dependent Stock Price Prediction Using Attention Modules and News Sentiment](https://mlsanity.com/paper/2205.01639/) (2022)

## Abstract (arXiv)

Multi-agent systems built on large language models (LLMs) require many coordination choices that are difficult to fix a priori: which skill protocol to invoke, which agent role should perform a subtask, which model to bind to each role, how roles should interact, when to use retrieval or verification, and when to omit a step entirely. These choices interact with task regime and operational constraints, so static pipelines and one-off model comparisons provide only a limited view of the design space. This paper introduces AgensFlow, an open-source framework that treats multi-agent coordination as an online policy-learning problem under partial observability. The framework makes coordination decisions observable and learnable from repeated trajectories, rather than treating skill, role, model, topology, and evaluation choices as fixed pipeline design. AgensFlow is evaluated on two corpora: distributed-systems incident tasks and security-advisory tasks. The evaluation shows three main results: learned routing reaches a higher-quality operating point than a fixed pipeline baseline on coordination-heavy classes; skip:X isolates topology compression as a meaningful part of the substrate; and warm-started policy graphs can reduce exploration cost while preserving plateau quality. Overall, the results support that learned, auditable routing can improve coordination-heavy multi-agent workflows over static wiring.