# Curation and Extraction of Drug-Related Entities from Reddit Platform

arXiv: https://arxiv.org/abs/2605.26445 · HTML: https://mlsanity.com/paper/2605.26445/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 14 of its 34 references that are in the map.
- First posted on arXiv 8 Apr 2026.

## Builds on (most cited first, 14 of 14)

- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [BioBERT: a pre-trained biomedical language representation model for biomedical text mining](https://mlsanity.com/paper/1901.08746/) (2019)
- [Domain-Specific Language Model Pretraining for Biomedical Natural Language Processing](https://mlsanity.com/paper/2007.15779/) (2020)
- [Bidirectional LSTM-CRF Models for Sequence Tagging](https://mlsanity.com/paper/1508.01991/) (2015)
- [GPT-NER: Named Entity Recognition via Large Language Models](https://mlsanity.com/paper/2304.10428/) (2023)
- [Towards Evaluating and Building Versatile Large Language Models for Medicine](https://mlsanity.com/paper/2408.12547/) (2024)
- [PromptNER: Prompting For Named Entity Recognition](https://mlsanity.com/paper/2305.15444/) (2023)
- [Wojood: Nested Arabic Named Entity Corpus and Recognition using BERT](https://mlsanity.com/paper/2205.09651/) (2022)
- [Reddit-Impacts: A Named Entity Recognition Dataset for Analyzing Clinical and Social Effects of Substance Use Derived from Social Media](https://mlsanity.com/paper/2405.06145/) (2024)
- [Fine-Tuning a Local LLaMA-3 Large Language Model for Automated Privacy-Preserving Physician Letter Generation in Radiation Oncology](https://mlsanity.com/paper/2408.10715/) (2024)
- [Learning In-context Learning for Named Entity Recognition](https://mlsanity.com/paper/2305.11038/) (2023)
- [W-procer: Weighted Prototypical Contrastive Learning for Medical Few-Shot Named Entity Recognition](https://mlsanity.com/paper/2305.18624/) (2023)

## Abstract (arXiv)

Physicians learn primarily about illicit drugs from clinical overdose cases, limiting their understanding of real-world usage. Meanwhile, drug users share first-hand experiences online, offering insights into dosage and effects of drugs. To bridge this gap, we introduce ReDose (REddit Drug DOSe and Effect), a dataset of 6,435 Reddit posts on substance use. A board-certified toxicologist primarily annotated both the training and test sets, while two medical science students contributed to the test set, labeling DRUG, DOSE, and EFFECT entities. We benchmarked 6,267 annotations using BERT-based, large language model (LLM)-based, and Retrieval-Augmented Generation (RAG) models. BiomedBERT achieved an F1-score of 0.843 for DRUG, while Llama-3 70B outperformed GPT-4 (F1 = 0.79 vs. 0.72). EFFECT extraction remains challenging, with GPT-4 achieving a recall of 0.41. ReDose captures patient-curated narratives to advance medical data extraction from social media.
