# Divide-Prompt-Refine: a Training-Free, Structure-Aware Framework for Biomedical Abstract Generation

arXiv: https://arxiv.org/abs/2605.20628 · HTML: https://mlsanity.com/paper/2605.20628/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 17 of its 45 references that are in the map.
- First posted on arXiv 20 May 2026.

## Builds on (most cited first, 17 of 17)

- [BERTScore: Evaluating Text Generation with BERT](https://mlsanity.com/paper/1904.09675/) (2019)
- [Longformer: The Long-Document Transformer](https://mlsanity.com/paper/2004.05150/) (2020)
- [Get To The Point: Summarization with Pointer-Generator Networks](https://mlsanity.com/paper/1704.04368/) (2017)
- [PubMedQA: A Dataset for Biomedical Research Question Answering](https://mlsanity.com/paper/1909.06146/) (2019)
- [Domain-Specific Language Model Pretraining for Biomedical Natural Language Processing](https://mlsanity.com/paper/2007.15779/) (2020)
- [A Discourse-Aware Attention Model for Abstractive Summarization of Long Documents](https://mlsanity.com/paper/1804.05685/) (2018)
- [SummaC: Re-Visiting NLI-based Models for Inconsistency Detection in Summarization](https://mlsanity.com/paper/2111.09525/) (2021)
- [Newsroom: A Dataset of 1.3 Million Summaries with Diverse Extractive Strategies](https://mlsanity.com/paper/1804.11283/) (2018)
- [AlignScore: Evaluating Factual Consistency with a Unified Alignment Function](https://mlsanity.com/paper/2305.16739/) (2023)
- [MiniCheck: Efficient Fact-Checking of LLMs on Grounding Documents](https://mlsanity.com/paper/2404.10774/) (2024)
- [ScispaCy: Fast and Robust Models for Biomedical Natural Language Processing](https://mlsanity.com/paper/1902.07669/) (2019)
- [LongT5: Efficient Text-To-Text Transformer for Long Sequences](https://mlsanity.com/paper/2112.07916/) (2021)
- [Does Prompt Formatting Have Any Impact on LLM Performance?](https://mlsanity.com/paper/2411.10541/) (2024)
- [PubMed 200k RCT: a Dataset for Sequential Sentence Classification in Medical Abstracts](https://mlsanity.com/paper/1710.06071/) (2017)
- [Pretrained Language Models for Sequential Sentence Classification](https://mlsanity.com/paper/1909.04054/) (2019)
- [Improving Biomedical Information Retrieval with Neural Retrievers](https://mlsanity.com/paper/2201.07745/) (2022)
- [CBAG: Conditional Biomedical Abstract Generation](https://mlsanity.com/paper/2002.05637/) (2020)

## Abstract (arXiv)

Biomedical abstracts play a critical role in downstream NLP applications, such as information retrieval, biocuration, and biomedical knowledge discovery. However, a non-trivial number of biomedical articles do not have abstracts, diminishing the utility of these articles for downstream tasks. We propose DPR-BAG (Divide, Prompt, and Refine for Biomedical Abstract Generation), a training-free, zero-shot framework that generates coherent and factually grounded abstracts for biomedical articles with full text but no abstract. DPR-BAG decomposes full-text documents into structured rhetorical facets following the Background-Objective-Methods-Results-Conclusions (BOMRC) schema, performs parallel LLM-based summarization for each facet, and applies a final refinement stage to restore global discourse coherence. On PMC-MAD, a distribution-aligned dataset of 46,309 biomedical articles, DPR-BAG improves abstractive novelty over strong extractive and fine-tuned baselines, while maintaining factual consistency. Our ablation study reveals a counterintuitive finding: increasing prompt complexity or explicitly injecting entity-level guidance can degrade factual alignment, highlighting the importance of controlled prompting strategies. These findings underscore the potential of training-free, structure-aware frameworks for scalable biomedical abstract generation in low-resource settings. Our data and code are available at https://huggingface.co/datasets/pmc-mad/PMC-MAD and https://github.com/ScienceNLP-Lab/MultiTagger-v2/tree/main/DPR-BAG.