# Do No Harm? Hallucination and Actor-Level Abuse in Web-Deployed Medical Large Language Models

arXiv: https://arxiv.org/abs/2605.20591 · HTML: https://mlsanity.com/paper/2605.20591/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 35 of its 57 references that are in the map.
- First posted on arXiv 20 May 2026.

## Builds on (most cited first, 30 of 35)

- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [G-Eval: NLG Evaluation using GPT-4 with Better Human Alignment](https://mlsanity.com/paper/2303.16634/) (2023)
- [Large Language Models Encode Clinical Knowledge](https://mlsanity.com/paper/2212.13138/) (2022)
- [A Survey on Hallucination in Large Language Models: Principles, Taxonomy, Challenges, and Open Questions](https://mlsanity.com/paper/2311.05232/) (2023)
- [A Survey on LLM-as-a-Judge](https://mlsanity.com/paper/2411.15594/) (2024)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [Galactica: A Large Language Model for Science](https://mlsanity.com/paper/2211.09085/) (2022)
- [BARTScore: Evaluating Generated Text as Text Generation](https://mlsanity.com/paper/2106.11520/) (2021)
- [ChatDoctor: A Medical Chat Model Fine-Tuned on a Large Language Model Meta-AI (LLaMA) Using Medical Domain Knowledge](https://mlsanity.com/paper/2303.14070/) (2023)
- [BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domains](https://mlsanity.com/paper/2402.10373/) (2024)
- [RARR: Researching and Revising What Language Models Say, Using Language Models](https://mlsanity.com/paper/2210.08726/) (2022)
- [MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Data](https://mlsanity.com/paper/2304.08247/) (2023)
- [A Stitch in Time Saves Nine: Detecting and Mitigating Hallucinations of LLMs by Validating Low-Confidence Generation](https://mlsanity.com/paper/2307.03987/) (2023)
- [A Survey of Large Language Models for Healthcare: from Data, Technology, and Applications to Accountability and Ethics](https://mlsanity.com/paper/2310.05694/) (2023)
- [Med-HALT: Medical Domain Hallucination Test for Large Language Models](https://mlsanity.com/paper/2307.15343/) (2023)
- [A Survey of Large Language Models in Medicine: Progress, Application, and Challenge](https://mlsanity.com/paper/2311.05112/) (2023)
- [Zhongjing: Enhancing the Chinese Medical Capabilities of Large Language Model through Expert Feedback and Real-world Multi-turn Dialogue](https://mlsanity.com/paper/2308.03549/) (2023)
- [Medical Hallucinations in Foundation Models and Their Impact on Healthcare](https://mlsanity.com/paper/2503.05777/) (2025)
- [HalluLens: LLM Hallucination Benchmark](https://mlsanity.com/paper/2504.17550/) (2025)
- [PMC-LLaMA: Towards Building Open-source Language Models for Medicine](https://mlsanity.com/paper/2304.14454/) (2023)
- [BioBART: Pretraining and Evaluation of A Biomedical Generative Language Model](https://mlsanity.com/paper/2204.03905/) (2022)
- [Apollo: A Lightweight Multilingual Medical LLM towards Democratizing Medical AI to 6B People](https://mlsanity.com/paper/2403.03640/) (2024)
- [Addressing cognitive bias in medical language models](https://mlsanity.com/paper/2402.08113/) (2024)
- [A Survey on Medical Large Language Models: Technology, Application, Trustworthiness, and Future Directions](https://mlsanity.com/paper/2406.03712/) (2024)
- [Creating Trustworthy LLMs: Dealing with Hallucinations in Healthcare AI](https://mlsanity.com/paper/2311.01463/) (2023)
- [JMLR: Joint Medical LLM and Retrieval Training for Enhancing Reasoning and Professional Question Answering Capability](https://mlsanity.com/paper/2402.17887/) (2024)
- [Polaris: A Safety-focused LLM Constellation Architecture for Healthcare](https://mlsanity.com/paper/2403.13313/) (2024)
- [MedHalu: Hallucinations in Responses to Healthcare Queries by Large Language Models](https://mlsanity.com/paper/2409.19492/) (2024)
- [Aloe: A Family of Fine-tuned Open Healthcare LLMs](https://mlsanity.com/paper/2405.01886/) (2024)
- [Health-LLM: Personalized Retrieval-Augmented Disease Prediction System](https://mlsanity.com/paper/2402.00746/) (2024)

## Abstract (arXiv)

Medical large language models (LLMs), including custom medical GPTs (MedGPTs) and open-source models, are increasingly deployed on web platforms to provide clinical guidance. However, they pose risks of hallucination, policy noncompliance, and unsafe design. We conduct a large-scale assessment of 6,233 MedGPTs, evaluating a stratified sample of 1,500, together with 10 open-source LLMs. We introduce two frameworks: MedGPT-HEval for hallucination detection and an LLM-based pipeline for assessing policy violations and developer intent. Our results show that 25-30% of MedGPTs exhibit low factual accuracy, with bottom- and middle-tier models at highest risk; 33.6-54.3% violate operational thresholds, and 57.06% of Action-enabled models lack adequate privacy disclosures. Compared with open-source models, MedGPTs achieve higher factual accuracy and semantic alignment, though open-source models are more stable. These results reveal systemic gaps in hallucination and compliance, highlighting the need for multi-metric evaluation and stronger safeguards. We release HAA-MedGPT, a structured dataset that supports future research on the safety of web-facing medical LLMs.
