# A Comprehensive Comparison of Deep Learning Architectures for COVID-19 Classification on CT & X-ray Imagery

arXiv: https://arxiv.org/abs/2605.20445 · HTML: https://mlsanity.com/paper/2605.20445/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 10 of its 34 references that are in the map.
- First posted on arXiv 19 May 2026.

## Builds on (most cited first, 10 of 10)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [MobileNets: Efficient Convolutional Neural Networks for Mobile Vision Applications](https://mlsanity.com/paper/1704.04861/) (2017)
- [COVID-Net: A Tailored Deep Convolutional Neural Network Design for Detection of COVID-19 Cases from Chest X-Ray Images](https://mlsanity.com/paper/2003.09871/) (2020)
- [CoroNet: A deep neural network for detection and diagnosis of COVID-19 from chest x-ray images](https://mlsanity.com/paper/2004.04931/) (2020)
- [Unveiling COVID-19 from Chest X-ray with deep learning: a hurdles race with small data](https://mlsanity.com/paper/2004.05405/) (2020)
- [CVR-Net: A deep convolutional neural network for coronavirus recognition from chest radiography images](https://mlsanity.com/paper/2007.11993/) (2020)
- [Classification of COVID-19 in CT Scans using Multi-Source Transfer Learning](https://mlsanity.com/paper/2009.10474/) (2020)

## Abstract (arXiv)

COVID-19 was a significant challenge that led to the loss of numerous lives daily. Not only a certain country was involved in this outbreak, but even the world has suffered because of the coronavirus. Imaging techniques using computed tomography (CT) and X-rays of the lungs are the most useful tools for the COVID-19 or any other pandemic disease screening process. Technology today has revolutionized the world by using artificial intelligence to replace manual processes with automated machines, which enable the system to imitate the human brain by making wise decisions based on experience. Motivated by this, our work proposes to use convolutional neural networks (CNN) based models for designing a computer-aided diagnosis (CAD) system that differentiates between COVID-19 and healthy lung pictures. We used two different sets of X-ray images of the lungs in addition to two different sets of CT scans and the classification is done using a variety of networks that have been pre-trained such as VGG (16, 19), Densenet (121), Resnet (50, 50 V2, 101 V2), Mobile net (V2), Xception Inception (V3, Resnet V2), Efficient net (B0) and Nasnet (Large). On the X-ray and CT image datasets, Resnet and VGG architecture have shown the ability to properly differentiate COVID-19 from normal images, with an average accuracy of 95 to 98 percent respectively. Our acquired results on the classification datasets are competitive and superior to previously reported findings in the literature.