# Learning Transferable Topology Priors for Multi-Agent LLM Collaboration Across Domains

arXiv: https://arxiv.org/abs/2605.17359 · HTML: https://mlsanity.com/paper/2605.17359/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Placed in General LLM agent frameworks and benchmarks, one of 16 directions in LLM agents and tool use.
- Builds on 44 of its 60 references that are in the map.
- First posted on arXiv 17 May 2026.

## Placed in

- LLM agents and tool use / [General LLM agent frameworks and benchmarks](https://mlsanity.com/agents/general-llm-agent-frameworks-and-benchmarks/)

## Builds on (most cited first, 30 of 44)

- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [Semi-Supervised Classification with Graph Convolutional Networks](https://mlsanity.com/paper/1609.02907/) (2016)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [Qwen2.5 Technical Report](https://mlsanity.com/paper/2412.15115/) (2024)
- [Empirical Evaluation of Gated Recurrent Neural Networks on Sequence Modeling](https://mlsanity.com/paper/1412.3555/) (2014)
- [AutoGen: Enabling Next-Gen LLM Applications via Multi-Agent Conversation](https://mlsanity.com/paper/2308.08155/) (2023)
- [Unsupervised Domain Adaptation by Backpropagation](https://mlsanity.com/paper/1409.7495/) (2014)
- [MetaGPT: Meta Programming for A Multi-Agent Collaborative Framework](https://mlsanity.com/paper/2308.00352/) (2023)
- [Improving Factuality and Reasoning in Language Models through Multiagent Debate](https://mlsanity.com/paper/2305.14325/) (2023)
- [Variational Graph Auto-Encoders](https://mlsanity.com/paper/1611.07308/) (2016)
- [ChatDev: Communicative Agents for Software Development](https://mlsanity.com/paper/2307.07924/) (2023)
- [C-Eval: A Multi-Level Multi-Discipline Chinese Evaluation Suite for Foundation Models](https://mlsanity.com/paper/2305.08322/) (2023)
- [LLM-Blender: Ensembling Large Language Models with Pairwise Ranking and Generative Fusion](https://mlsanity.com/paper/2306.02561/) (2023)
- [A Dynamic LLM-Powered Agent Network for Task-Oriented Agent Collaboration](https://mlsanity.com/paper/2310.02170/) (2023)
- [Exploring Collaboration Mechanisms for LLM Agents: A Social Psychology View](https://mlsanity.com/paper/2310.02124/) (2023)
- [Fine-tuned Language Models are Continual Learners](https://mlsanity.com/paper/2205.12393/) (2022)
- [Cut the Crap: An Economical Communication Pipeline for LLM-based Multi-Agent Systems](https://mlsanity.com/paper/2410.02506/) (2024)
- [M3CoT: A Novel Benchmark for Multi-Domain Multi-step Multi-modal Chain-of-Thought](https://mlsanity.com/paper/2405.16473/) (2024)
- [G-Designer: Architecting Multi-agent Communication Topologies via Graph Neural Networks](https://mlsanity.com/paper/2410.11782/) (2024)
- [A Comprehensive Survey on Source-free Domain Adaptation](https://mlsanity.com/paper/2302.11803/) (2023)
- [Self-Organized Agents: A LLM Multi-Agent Framework toward Ultra Large-Scale Code Generation and Optimization](https://mlsanity.com/paper/2404.02183/) (2024)
- [How to Read Paintings: Semantic Art Understanding with Multi-Modal Retrieval](https://mlsanity.com/paper/1810.09617/) (2018)
- [Assemble Your Crew: Automatic Multi-agent Communication Topology Design via Autoregressive Graph Generation](https://mlsanity.com/paper/2507.18224/) (2025)
- [Understanding the Dark Side of LLMs' Intrinsic Self-Correction](https://mlsanity.com/paper/2412.14959/) (2024)
- [Multi-Prompt Alignment for Multi-Source Unsupervised Domain Adaptation](https://mlsanity.com/paper/2209.15210/) (2022)
- [Attribution-aware Weight Transfer: A Warm-Start Initialization for Class-Incremental Semantic Segmentation](https://mlsanity.com/paper/2210.07207/) (2022)

## Built on by (most cited first, 2 of 2)

- [Evo2Team: When Do Evolved Skills Transfer? From Selection to Deployment](https://mlsanity.com/paper/2609.34135/) (2026)
- [WorkflowOps: Learning Agent Collaboration Priors for Multi-Agent Workflow Orchestration](https://mlsanity.com/paper/2610.07860/) (2026)

## Abstract (arXiv)

Large language model (LLM)-based multi-agent systems have shown strong potential for complex reasoning by coordinating specialized agents through structured communication. However, existing topology-evolution methods typically construct or optimize a collaboration topology for each query from scratch, leading to substantial online search overhead, high inference-time token consumption, and limited scalability in multi-domain settings. We propose TopoPrior, a framework for learning transferable topology priors for multi-agent LLM collaboration across domains. Rather than repeatedly searching for effective collaboration structures online, TopoPrior learns reusable topology priors from reference collaboration graphs collected offline from multiple domains and uses them to generate query-conditioned initial collaboration graphs for downstream refinement. By shifting part of topology search from per-query online optimization to offline prior learning, TopoPrior amortizes search cost while remaining compatible with existing topology-evolution backbones. Technically, TopoPrior contains two key components. First, a transferable topology prior learning module employs a conditional variational graph framework to capture reusable structural regularities across domains in a latent space. Second, a query-conditioned latent adaptation module introduces adversarial alignment to reduce unnecessary domain discrepancy while preserving query-relevant structural variation. Experiments on multi-domain reasoning benchmarks show that TopoPrior consistently improves several heterogeneous topology-evolution backbones while reducing online inference-time token usage, with only modest additional trainable parameters. These results suggest that transferable topology initialization is an effective and lightweight mechanism for improving the efficiency of multi-agent LLM collaboration across domains.