# CHI-Bench: Can AI Agents Automate End-to-End, Long-Horizon, Policy-Rich Healthcare Workflows?

arXiv: https://arxiv.org/abs/2605.16679 · HTML: https://mlsanity.com/paper/2605.16679/

## Key facts

- Cited by 8 papers in the map (data through 14 Oct 2026).
- Builds on 32 of its 62 references that are in the map.
- First posted on arXiv 15 May 2026.

## Builds on (most cited first, 30 of 32)

- [Qwen3 Technical Report](https://mlsanity.com/paper/2505.09388/) (2025)
- [Evaluating Large Language Models Trained on Code](https://mlsanity.com/paper/2107.03374/) (2021)
- [SWE-bench: Can Language Models Resolve Real-World GitHub Issues?](https://mlsanity.com/paper/2310.06770/) (2023)
- [WebArena: A Realistic Web Environment for Building Autonomous Agents](https://mlsanity.com/paper/2307.13854/) (2023)
- [τ-bench: A Benchmark for Tool-Agent-User Interaction in Real-World Domains](https://mlsanity.com/paper/2406.12045/) (2024)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [PubMedQA: A Dataset for Biomedical Research Question Answering](https://mlsanity.com/paper/1909.06146/) (2019)
- [OSWorld: Benchmarking Multimodal Agents for Open-Ended Tasks in Real Computer Environments](https://mlsanity.com/paper/2404.07972/) (2024)
- [τ2-Bench: Evaluating Conversational Agents in a Dual-Control Environment](https://mlsanity.com/paper/2506.07982/) (2025)
- [GLM-5: from Vibe Coding to Agentic Engineering](https://mlsanity.com/paper/2602.15763/) (2026)
- [Terminal-Bench: Benchmarking Agents on Hard, Realistic Tasks in Command Line Interfaces](https://mlsanity.com/paper/2601.11868/) (2026)
- [Kimi K2: Open Agentic Intelligence](https://mlsanity.com/paper/2507.20534/) (2025)
- [MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answering](https://mlsanity.com/paper/2203.14371/) (2022)
- [HealthBench: Evaluating Large Language Models Towards Improved Human Health](https://mlsanity.com/paper/2505.08775/) (2025)
- [AppWorld: A Controllable World of Apps and People for Benchmarking Interactive Coding Agents](https://mlsanity.com/paper/2407.18901/) (2024)
- [WorkArena: How Capable Are Web Agents at Solving Common Knowledge Work Tasks?](https://mlsanity.com/paper/2403.07718/) (2024)
- [Benchmarking Retrieval-Augmented Generation for Medicine](https://mlsanity.com/paper/2402.13178/) (2024)
- [TheAgentCompany: Benchmarking LLM Agents on Consequential Real World Tasks](https://mlsanity.com/paper/2412.14161/) (2024)
- [SkillsBench: Benchmarking How Well Agent Skills Work Across Diverse Tasks](https://mlsanity.com/paper/2602.12670/) (2026)
- [AgentClinic: a multimodal agent benchmark to evaluate AI in simulated clinical environments](https://mlsanity.com/paper/2405.07960/) (2024)
- [MedXpertQA: Benchmarking Expert-Level Medical Reasoning and Understanding](https://mlsanity.com/paper/2501.18362/) (2025)
- [EHRSHOT: An EHR Benchmark for Few-Shot Evaluation of Foundation Models](https://mlsanity.com/paper/2307.02028/) (2023)
- [The Tool Decathlon: Benchmarking Language Agents for Diverse, Realistic, and Long-Horizon Task Execution](https://mlsanity.com/paper/2510.25726/) (2025)
- [MedCalc-Bench: Evaluating Large Language Models for Medical Calculations](https://mlsanity.com/paper/2406.12036/) (2024)
- [MedHELM: Holistic Evaluation of Large Language Models for Medical Tasks](https://mlsanity.com/paper/2505.23802/) (2025)
- [EHRSQL: A Practical Text-to-SQL Benchmark for Electronic Health Records](https://mlsanity.com/paper/2301.07695/) (2023)
- [MedicalAgentsBench for Complex Medical Reasoning: Comparing Internalized Reasoning Models versus Externalized Agent-based Frameworks](https://mlsanity.com/paper/2503.07459/) (2025)
- [BioCoder: A Benchmark for Bioinformatics Code Generation with Large Language Models](https://mlsanity.com/paper/2308.16458/) (2023)
- [MedAgentGym: A Scalable Agentic Training Environment for Code-Centric Reasoning in Biomedical Data Science](https://mlsanity.com/paper/2506.04405/) (2025)
- [Medchain: Bridging the Gap Between LLM Agents and Clinical Practice with Interactive Sequence](https://mlsanity.com/paper/2412.01605/) (2024)

## Built on by (most cited first, 8 of 8)

- [Locating Hidden Failures Makes Long-Horizon Agents More Reliable](https://mlsanity.com/paper/2609.17930/) (2026)
- [The Path to Self-Evolving Clinical Systems: Scaling Medical Agents from Assistance to Autonomy](https://mlsanity.com/paper/2607.11175/) (2026)
- [GDPevo: Evaluating Agent Self-Evolution on Real Business Tasks](https://mlsanity.com/paper/2608.03764/) (2026)
- [Cura 1T: Specialized Model for Agentic Healthcare](https://mlsanity.com/paper/2607.15314/) (2026)
- [Natural-Language Workflows Are Not Software Yet: Artifact-Driven Compilation for Reliable Agent Execution](https://mlsanity.com/paper/2608.21341/) (2026)
- [ExecRubrics: Executable Tool-Augmented Rubrics for Verifiable and Efficient Long-Form Evaluation](https://mlsanity.com/paper/2608.22559/) (2026)
- [MedicalHarness: A Controlled Evaluation of LLMs and Agent Harnesses on Medical Tasks](https://mlsanity.com/paper/2610.05778/) (2026)
- [MedHarnessBench: A Unified Benchmark for Healthcare Agent Evaluation](https://mlsanity.com/paper/2610.15714/) (2026)

## Abstract (arXiv)

End-to-end automation of realistic healthcare operations stresses three capabilities underrepresented in current benchmarks: policy density, decisions must be grounded in a large library of medical, insurance, and operational rules; Multi-role composition: a single task requires the agent to play multiple roles with handoffs; and multilateral interaction: intermediate workflow steps are multi-turn dialogs, such as peer-to-peer review and patient outreach. We introduce chi-Bench, a benchmark of long-horizon healthcare workflows across three domains: provider prior authorization, payer utilization management, and care management. Each task hands the agent a clinical case in a high-fidelity simulator of 20 healthcare apps exposed via 87 MCP tools, which it must drive to a terminal status through tool calls and writing the role's artifacts, guided by a 1,290+ document managed-care operations handbook skill. Across 30 agent harness/models configurations, the best agent resolves only 28.0% of tasks, no agent clears 20% on strict pass3, and executing all tasks in a single session slumps the performance to 3.8%. These results raise the hypothesis that similar gaps are likely to surface in other policy-dense, role-composed, irreversible enterprise domains.
