# Imitation learning for clinical decision support in pediatric ECMO

arXiv: https://arxiv.org/abs/2605.16175 · HTML: https://mlsanity.com/paper/2605.16175/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Safe offline RL, one of 13 directions in Offline RL and imitation learning from data.
- Builds on 5 of its 11 references that are in the map.
- First posted on arXiv 15 May 2026.

## Placed in

- Offline RL and imitation learning from data / [Safe offline RL](https://mlsanity.com/offlinerl/safe-offline-rl/)

## Builds on (most cited first, 5 of 5)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [XGBoost: A Scalable Tree Boosting System](https://mlsanity.com/paper/1603.02754/) (2016)
- [TabPFN: A Transformer That Solves Small Tabular Classification Problems in a Second](https://mlsanity.com/paper/2207.01848/) (2022)
- [TabPFN-2.5: Advancing the State of the Art in Tabular Foundation Models](https://mlsanity.com/paper/2511.08667/) (2025)
- [Generative Artificial Intelligence: A Systematic Review and Applications](https://mlsanity.com/paper/2405.11029/) (2024)

## Abstract (arXiv)

Pediatric critical care is a dynamic, high-stakes process involving constant monitoring and adjustments in life-saving treatments. Modeling these interventions is crucial for effective decision support. To address the challenges of high complexity and data scarcity in pediatric Extracorporeal Membrane Oxygenation (ECMO), we frame clinical decision-making as learning to act from trajectories, i.e., imitation learning that learns action models from observational data, with a key feature that actions are not directly observed. We consider TabPFN, a recent transformer-based approach for tabular data, and traditional baselines including XGBoost and Multi-Layer Perceptrons(MLPs) on real-world pediatric ECMO data to learn the action models. We find that the TabPFN-based approach consistently outperforms these classical baselines, supporting its use as a strong clinician-behavior baseline for pediatric ECMO decision support.