# Uncertainty-Driven Anomaly Detection for Psychotic Relapse Using Smartwatches: Forecasting and Multi-Task Learning Fusion

arXiv: https://arxiv.org/abs/2605.13816 · HTML: https://mlsanity.com/paper/2605.13816/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 2 of its 19 references that are in the map.
- First posted on arXiv 13 May 2026.

## Builds on (most cited first, 2 of 2)

- [RoFormer: Enhanced Transformer with Rotary Position Embedding](https://mlsanity.com/paper/2104.09864/) (2021)
- [Train Short, Test Long: Attention with Linear Biases Enables Input Length Extrapolation](https://mlsanity.com/paper/2108.12409/) (2021)

## Abstract (arXiv)

Digital phenotyping enables continuous passive monitoring of behavior and physiology, offering a promising paradigm for early detection of psychotic relapse. In this work, we develop and systematically study two smartwatch-based frameworks for daily relapse detection. The first forecasts cardiac dynamics and flags deviations between predicted and observed features as indicators of abnormality. The second adopts a multi-task formulation that fuses sleep with motion and cardiac-derived signals, learning time-aware embeddings and predicting measurement timing. Both pipelines use Transformer encoders and output a daily anomaly score, derived from predictive uncertainty estimated via an ensemble of multilayer perceptrons to improve robustness to real-world wearable variability. While each framework independently demonstrates strong predictive power, we show that they capture complementary physiological signatures. Consequently, we propose a late-fusion strategy that synergistically combines the anomaly signals from both architectures into a unified decision score. We benchmark our methodology on the 2nd e-Prevention Grand Challenge dataset, where our fused model achieves a 8% relative improvement over the competition-winning baseline. Our results, supported by extensive ablation studies, suggest that the integration of diverse digital phenotypes, cardiac, motion, and sleep, is essential for the high-fidelity detection of psychotic relapse in real-world settings.