# Geometrically Constrained Stenosis Editing in Coronary Angiography via Entropic Optimal Transport

arXiv: https://arxiv.org/abs/2605.08851 · HTML: https://mlsanity.com/paper/2605.08851/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 30 of its 55 references that are in the map.
- First posted on arXiv 9 May 2026.

## Builds on (most cited first, 30 of 30)

- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [Adding Conditional Control to Text-to-Image Diffusion Models](https://mlsanity.com/paper/2302.05543/) (2023)
- [Image-to-Image Translation with Conditional Adversarial Networks](https://mlsanity.com/paper/1611.07004/) (2016)
- [Grounding DINO: Marrying DINO with Grounded Pre-Training for Open-Set Object Detection](https://mlsanity.com/paper/2303.05499/) (2023)
- [InstructPix2Pix: Learning to Follow Image Editing Instructions](https://mlsanity.com/paper/2211.09800/) (2022)
- [Prompt-to-Prompt Image Editing with Cross Attention Control](https://mlsanity.com/paper/2208.01626/) (2022)
- [Sinkhorn Distances: Lightspeed Computation of Optimal Transportation Distances](https://mlsanity.com/paper/1306.0895/) (2013)
- [SDEdit: Guided Image Synthesis and Editing with Stochastic Differential Equations](https://mlsanity.com/paper/2108.01073/) (2021)
- [T2I-Adapter: Learning Adapters to Dig out More Controllable Ability for Text-to-Image Diffusion Models](https://mlsanity.com/paper/2302.08453/) (2023)
- [DINO: DETR with Improved DeNoising Anchor Boxes for End-to-End Object Detection](https://mlsanity.com/paper/2203.03605/) (2022)
- [Semantic Image Synthesis with Spatially-Adaptive Normalization](https://mlsanity.com/paper/1903.07291/) (2019)
- [High-Resolution Image Synthesis and Semantic Manipulation with Conditional GANs](https://mlsanity.com/paper/1711.11585/) (2017)
- [Diffusion Schr"odinger Bridge with Applications to Score-Based Generative Modeling](https://mlsanity.com/paper/2106.01357/) (2021)
- [Uni-ControlNet: All-in-One Control to Text-to-Image Diffusion Models](https://mlsanity.com/paper/2305.16322/) (2023)
- [A survey of the Schr"odinger problem and some of its connections with optimal transport](https://mlsanity.com/paper/1308.0215/) (2013)
- [BBDM: Image-to-image Translation with Brownian Bridge Diffusion Models](https://mlsanity.com/paper/2205.07680/) (2022)
- [I2SB: Image-to-Image Schr"odinger Bridge](https://mlsanity.com/paper/2302.05872/) (2023)
- [Dual Diffusion Implicit Bridges for Image-to-Image Translation](https://mlsanity.com/paper/2203.08382/) (2022)
- [RTMDet: An Empirical Study of Designing Real-Time Object Detectors](https://mlsanity.com/paper/2212.07784/) (2022)
- [Semantic Image Synthesis via Diffusion Models](https://mlsanity.com/paper/2207.00050/) (2022)
- [Unpaired Image-to-Image Translation via Neural Schr"odinger Bridge](https://mlsanity.com/paper/2305.15086/) (2023)
- [Conditional Diffusion Models for Semantic 3D Brain MRI Synthesis](https://mlsanity.com/paper/2305.18453/) (2023)
- [Anatomically-Controllable Medical Image Generation with Segmentation-Guided Diffusion Models](https://mlsanity.com/paper/2402.05210/) (2024)
- [DiffMix: Diffusion Model-based Data Synthesis for Nuclei Segmentation and Classification in Imbalanced Pathology Image Datasets](https://mlsanity.com/paper/2306.14132/) (2023)
- [Noise-Consistent Siamese-Diffusion for Medical Image Synthesis and Segmentation](https://mlsanity.com/paper/2505.06068/) (2025)
- [A Dimension-free Computational Upper-bound for Smooth Optimal Transport Estimation](https://mlsanity.com/paper/2101.05380/) (2021)
- [Ambiguous Medical Image Segmentation Using Diffusion Schr"odinger Bridge](https://mlsanity.com/paper/2509.17187/) (2025)
- [Diffusion-Based User-Guided Data Augmentation for Coronary Stenosis Detection](https://mlsanity.com/paper/2508.00438/) (2025)
- [Diffusion-Based Data Augmentation for Medical Image Segmentation](https://mlsanity.com/paper/2508.17844/) (2025)
- [MedShift: Implicit Conditional Transport for X-Ray Domain Adaptation](https://mlsanity.com/paper/2508.21435/) (2025)

## Built on by (most cited first, 1 of 1)

- [VDSB-GWSyn: Diffusion Schr"odinger Bridge for Controllable and Anatomically Feasible Guidewire Synthesis in Coronary Angiography](https://mlsanity.com/paper/2606.00109/) (2026)

## Abstract (arXiv)

The scarcity of high-quality imaging data for coronary angiography (CAG) stenosis limits the clinical translation of automated stenosis detection. Synthetic stenosis data provides a practical avenue to augment training sets, improving data quality, diversity, and distributional coverage, and enhancing detection precision and generalization. However, diffusion-based editing commonly relies on soft guidance in a noise-initialized reverse process, offering limited pixel-level precision and structure preservation. We propose the OT-Bridge Editor, which reframes localized editing as a constrained entropic optimal transport (OT) problem and leverages geometric information to steer the generation path, enabling stronger geometric control. Extensive experiments show that our synthesized angiograms consistently improve downstream stenosis detection, yielding substantial relative gains of 27.8% on the public ARCADE benchmark and 23.0% on our multi-center dataset, supported by consistent qualitative results.