# SAMamba3D: adapting Segment Anything for generalizable 3D segmentation of multiphase pore-scale images

arXiv: https://arxiv.org/abs/2605.00916 · HTML: https://mlsanity.com/paper/2605.00916/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 10 of its 49 references that are in the map.
- First posted on arXiv 29 Apr 2026.

## Builds on (most cited first, 10 of 10)

- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [Mamba: Linear-Time Sequence Modeling with Selective State Spaces](https://mlsanity.com/paper/2312.00752/) (2023)
- [FiLM: Visual Reasoning with a General Conditioning Layer](https://mlsanity.com/paper/1709.07871/) (2017)
- [Swin UNETR: Swin Transformers for Semantic Segmentation of Brain Tumors in MRI Images](https://mlsanity.com/paper/2201.01266/) (2022)
- [Medical SAM Adapter: Adapting Segment Anything Model for Medical Image Segmentation](https://mlsanity.com/paper/2304.12620/) (2023)
- [U-Mamba: Enhancing Long-range Dependency for Biomedical Image Segmentation](https://mlsanity.com/paper/2401.04722/) (2024)
- [3D MRI brain tumor segmentation using autoencoder regularization](https://mlsanity.com/paper/1810.11654/) (2018)
- [Tversky loss function for image segmentation using 3D fully convolutional deep networks](https://mlsanity.com/paper/1706.05721/) (2017)
- [MA-SAM: Modality-agnostic SAM Adaptation for 3D Medical Image Segmentation](https://mlsanity.com/paper/2309.08842/) (2023)

## Abstract (arXiv)

Reliable segmentation of multiphase pore-scale X-ray images of rocks is necessary to quantify fluid saturation, connectivity, and interfacial geometry. However, current 3D segmentation methods are typically dataset-specific, requiring retraining or extensive fine-tuning whenever rock type, fluid pattern, scanner, or acquisition conditions change. Foundation models such as the Segment Anything Model (SAM) provide strong 2D boundary priors, but they are not directly applicable to 3D data. We present SAMamba3D, a parameter-efficient framework that adapts a largely frozen SAM encoder to generalizable 3D pore-scale segmentation by coupling it with Mamba-based volumetric context modeling and progressive cross-scale feature interaction. For sandstone and carbonate datasets, with different fluids, wettability, and scanning conditions, SAMamba3D matches or outperforms current 3D baselines while reducing the need for case-specific retraining. The resulting segmented images preserve physically meaningful descriptors, including fluid saturation, connectivity, and interface morphology, enabling more reliable and rapid analysis of large 3D multiphase images.